JAK-STAT pathway activation in COPD

被引：65
作者：
Yew-Booth, Liang [1 ]
Birrell, Mark A. [1 ]
Lau, Ming Sum [1 ]
Baker, Katie [1 ]
Jones, Victoria [1 ]
Kilty, Iain [2 ]
Belvisi, Maria G. [1 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, Resp Pharmacol, Fac Med, London SW7 2AZ, England
[2] Pfizer Inc, Cambridge, MA USA
来源：
EUROPEAN RESPIRATORY JOURNAL | 2015年 / 46卷 / 03期
基金：
英国医学研究理事会;
关键词：
OBSTRUCTIVE PULMONARY-DISEASE;
D O I：
10.1183/09031936.00228414
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
引用
收藏
页码：843 / 845
页数：3
相关论文
共 50 条
  • [1] Cigarette smoke-induced lung inflammation in COPD mediated via CCR1/JAK/STAT/NF-κB pathway
    Zhao, Kaishun
    Dong, Ran
    Yu, Yanfang
    Tu, Chunlin
    Li, Ying
    Cui, YuJuan
    Bao, Lei
    Ling, Chunhua
    AGING-US, 2020, 12 (10): : 9125 - 9138
  • [2] Acute nitrogen dioxide (NO2) exposure enhances airway inflammation via modulating Th1/Th2 differentiation and activating JAK-STAT pathway
    Ji, Xiaotong
    Han, Ming
    Yun, Yang
    Li, Guangke
    Sang, Nan
    CHEMOSPHERE, 2015, 120 : 722 - 728
  • [3] Sequential inspiratory muscle exercise-noninvasive positive pressure ventilation alleviates oxidative stress in COPD by mediating SOCS5/JAK2/STAT3 pathway
    Lei, Yirou
    He, Jiaying
    Hu, Fang
    Zhu, Hao
    Gu, Jing
    Tang, Lijuan
    Luo, Man
    BMC PULMONARY MEDICINE, 2023, 23 (01)
  • [4] IFN-γ-induced JAK/STAT, but not NF-κB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells
    O'Connell, Danielle
    Bouazza, Belaid
    Kokalari, Blerina
    Amrani, Yassine
    Khatib, Alaa
    Ganther, John David
    Tliba, Omar
    AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2015, 309 (04) : L348 - L359
  • [5] Impaired exercise training-induced muscle fiber hypertrophy and Akt/mTOR pathway activation in hypoxemic patients with COPD
    Costes, Frederic
    Gosker, Harry
    Feasson, Leonard
    Desgeorges, Marine
    Kelders, Marco
    Castells, Josiane
    Schols, Annemie
    Freyssenet, Damien
    JOURNAL OF APPLIED PHYSIOLOGY, 2015, 118 (08) : 1040 - 1049
  • [6] Oxidation pathway and exacerbations in COPD: the role of NAC
    Matera, Maria Gabriella
    Calzetta, Luigino
    Cazzola, Mario
    EXPERT REVIEW OF RESPIRATORY MEDICINE, 2016, 10 (01) : 89 - 97
  • [7] Developing a Multidisciplinary Approach to the COPD Care Pathway
    Young, Meilin
    Villgran, Vipin
    Ledgerwood, Chelsea
    Schmetzer, Amy
    Cheema, Tariq
    CRITICAL CARE NURSING QUARTERLY, 2021, 44 (01) : 121 - 127
  • [8] Sympathetic Activation is Associated with Exercise Limitation in COPD
    Haarmann, Helge
    Folle, Jan
    Xuan Phuc Nguyen
    Herrmann, Peter
    Heusser, Karsten
    Hasenfuss, Gerd
    Andreas, Stefan
    Raupach, Tobias
    COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2016, 13 (05) : 589 - 594
  • [9] Role of the Fungus Pneumocystis in IL1β Pathway Activation and Airways Collagen Deposition in Elastase-Induced COPD Animals
    Coronado, Krishna
    Herrada, Carla
    Rojas, Diego A.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (06)
  • [10] IFN-γ synergistically enhances LPS signalling in alveolar macrophages from COPD patients and controls by corticosteroid-resistant STAT1 activation
    Southworth, T.
    Metryka, A.
    Lea, S.
    Farrow, S.
    Plumb, J.
    Singh, D.
    BRITISH JOURNAL OF PHARMACOLOGY, 2012, 166 (07) : 2070 - 2083
12345