Endothelial progenitor cells and erectile dysfunction: a brief review on diagnostic significance and summary of our experience

被引:13
作者
Condorelli, Rosita A. [1 ]
Calogero, Aldo E. [1 ]
Vicari, Enzo [1 ]
Duca, Ylenia [2 ]
Favilla, Vincenzo [2 ]
Morgia, Giuseppe [2 ]
Cimino, Sebastiano [2 ]
La Vignera, Sandro [1 ]
机构
[1] Univ Catania, Dept Med & Pediat Sci, I-95123 Catania, Italy
[2] Univ Catania, Dept Urol, Sect Endocrinol Androl & Internal Med, I-95123 Catania, Italy
关键词
Diagnostic value; endothelial progenitor cells; erectile dysfunction; LATE-ONSET HYPOGONADISM; METABOLIC SYNDROME; MICROPARTICLES; IMMUNOPHENOTYPE; RELIABILITY; MEN; ATHEROSCLEROSIS; ANDROGENS; CORRELATE; DISEASE;
D O I
10.3109/13685538.2013.789159
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The article provides a brief review of the literature concerning the diagnostic use of endothelial progenitor cells in patients with erectile dysfunction. In particular, patients with arterial erectile dysfunction could benefit from the use of this diagnostic marker, which in clinical practice can be used together with more conventional methods such as the penile Doppler. It is very important to acquire diagnostic tools for the diagnosis of sub clinical form of endothelial dysfunction in these patients, in particular when the erectile dysfunction is associated with cardiovascular risk factors.
引用
收藏
页码:29 / 32
页数:4
相关论文
共 26 条
[1]   Isolation of putative progenitor endothelial cells for angiogenesis [J].
Asahara, T ;
Murohara, T ;
Sullivan, A ;
Silver, M ;
vanderZee, R ;
Li, T ;
Witzenbichler, B ;
Schatteman, G ;
Isner, JM .
SCIENCE, 1997, 275 (5302) :964-967
[2]   Circulating endothelial progenitor cells correlate with erectile function in patients with coronary heart disease [J].
Baumhaekel, Magnus ;
Werner, Nikos ;
Boehm, Michael ;
Nickenig, Georg .
EUROPEAN HEART JOURNAL, 2006, 27 (18) :2184-2188
[3]   Arterial Erectile Dysfunction and Peripheral Arterial Disease: Reliability of a New Phenotype of Endothelial Progenitor Cells and Endothelial Microparticles [J].
Condorelli, Rosita A. ;
Calogero, Aldo E. ;
Vicari, Enzo ;
Di Pino, Luigi ;
Giacone, Filippo ;
Mongioi, Laura ;
La Vignera, Sandro .
JOURNAL OF ANDROLOGY, 2012, 33 (06) :1268-1275
[4]   Endothelial progenitor cells in atherosclerosis [J].
Du, Fuyong ;
Zhou, Jun ;
Gong, Ren ;
Huang, Xiao ;
Pansuria, Meghana ;
Virtue, Anthony ;
Li, Xinyuan ;
Wang, Hong ;
Yang, Xiao-Feng .
FRONTIERS IN BIOSCIENCE-LANDMARK, 2012, 17 :2327-2349
[5]   Circulating CD34+KDR+ Endothelial Progenitor Cells Correlate with Erectile Function and Endothelial Function in Overweight Men [J].
Esposito, Katherine ;
Ciotola, Miryam ;
Maiorino, Maria Ida ;
Giugliano, Francesco ;
Autorino, Riccardo ;
De Sio, Marco ;
Jannini, Emmanuele ;
Lenzi, Andrea ;
Giugliano, Dario .
JOURNAL OF SEXUAL MEDICINE, 2009, 6 (01) :107-114
[6]   Endothelial progenitor cells and erectile dysfunction [J].
Fadini, Gian Paolo ;
Agostini, Carlo ;
Avogaro, Angelo .
EUROPEAN HEART JOURNAL, 2007, 28 (05) :639-640
[7]   Reduced number of circulating endothelial progenitor cells in hypogonadal men [J].
Foresta, C. ;
Caretta, N. ;
Lana, A. ;
De Toni, L. ;
Biagioli, A. ;
Ferlin, A. ;
Garolla, A. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 91 (11) :4599-4602
[8]   Circulating endothelial progenitor cells and endothelial function after chronic Tadalafil treatment in subjects with erectile dysfunction [J].
Foresta, C. ;
Ferlin, A. ;
De Toni, L. ;
Lana, A. ;
Vinanzi, C. ;
Galan, A. ;
Caretta, N. .
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, 2006, 18 (05) :484-488
[9]   Circulating endothelial progenitor cells in subjects with erectile dysfunction [J].
Foresta, C ;
Caretta, N ;
Lana, A ;
Cabrelle, A ;
Palù, G ;
Ferlin, A .
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, 2005, 17 (03) :288-290
[10]   Androgens stimulate endothelial progenitor cells through an androgen receptor-mediated pathway [J].
Foresta, Carlo ;
Zuccarello, Daniela ;
De Toni, Luca ;
Garolla, Andrea ;
Caretta, Nicola ;
Ferlin, Alberto .
CLINICAL ENDOCRINOLOGY, 2008, 68 (02) :284-289