Synthesis and Antimicrobial Properties of Novel Silver/Polyrhodanine Nanofibers

被引:104
作者
Kong, Hyeyoung [1 ]
Jang, Jyongsik [1 ]
机构
[1] Seoul Natl Univ, Sch Chem & Biol Engn, Coll Engn, Seoul 151742, South Korea
关键词
D O I
10.1021/bm800574x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Silver nanoparticle-embedded polyrhodanine nanofibers were synthesized by chemical oxidation polymerization. Silver ions were reduced to silver nanoparticles by oxidizing rhodanine monomer and simultaneously complexed with the rhodanine due to coordinative interactions, resulting in the formation of silver nanoparticle-embedded polyrhodanine nanofibers. The synthesized silver/polyrhodanine nanofiber was found to have the excellent antimicrobial activity against Gram-negative Escherichia coli, Gram-positive Staphylococcus aureus, and Candida albicans. The modified Kirby-Bauer test demonstrated that the silver/polyrhodanine nanofiber had better antimicrobial efficacy than silver sulfadiazine.
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收藏
页码:2677 / 2681
页数:5
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