The aetiology of idiopathic Parkinson's disease

被引:0
|
作者
Ramsden, DB [1 ]
Parsons, RB
Ho, SL
Waring, RH
机构
[1] Univ Birmingham, Queen Elizabeth Hosp, Div Med Sci, Dept Med, Birmingham B15 2TH, W Midlands, England
[2] Univ Hong Kong, Div Neurol, Dept Med, Hong Kong, Hong Kong, Peoples R China
[3] Univ Birmingham, Sch Biochem, Birmingham B15 2TT, W Midlands, England
来源
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY | 2001年 / 54卷 / 06期
关键词
Parkinson's disease; environmental agents; transcription factors; alpha synuclein; parkin; ubiquitin carboxy terminal hydroxylase L1;
D O I
暂无
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Agents potentially involved in the aetiology of idiopathic Parkinson's disease are discussed. These include factors regulating dopaminergic neurogenesis (Nurr 1, Ptx-3, and Lmx1b) and related proteins, together with genes involved in familial Parkinson's disease (alpha synuclein, parkin, and ubiquitin carboxy terminal hydroxylase L1), and endogenous and environmental agents.
引用
收藏
页码:369 / 380
页数:12
相关论文
共 50 条
  • [1] Aetiology of Parkinson's disease
    Brown, S
    NEW ZEALAND MEDICAL JOURNAL, 1997, 110 (1045) : 216 - 217
  • [2] Parkinson's disease: Biology and aetiology
    Temlett, JA
    CURRENT OPINION IN NEUROLOGY, 1996, 9 (04) : 303 - 307
  • [3] Mitochondria in the aetiology and pathogenesis of Parkinson's disease
    Schapira, Anthony H. V.
    LANCET NEUROLOGY, 2008, 7 (01): : 97 - 109
  • [4] Mitochondria in the aetiology and pathogenesis of Parkinson's disease
    Schapira, AHV
    PARKINSONISM & RELATED DISORDERS, 1999, 5 (04) : 139 - 143
  • [5] Aetiology of Parkinson's Disease: Braak revisited
    Pan-Montojo, F. J.
    Reichmann, H.
    AKTUELLE NEUROLOGIE, 2014, 41 (10) : 573 - 578
  • [6] Parkinson's disease - pathology, aetiology and diagnosis
    Macphee, Graeme J. A.
    Stewart, David A.
    REVIEWS IN CLINICAL GERONTOLOGY, 2012, 22 (03) : 165 - 178
  • [7] Idiopathic Parkinson's disease
    Vieregge, P.
    FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE, 2008, 76 (02) : 114 - 122
  • [8] The aetiology and management of sleep episodes in Parkinson's disease
    Schapira, AHV
    EUROPEAN JOURNAL OF NEUROLOGY, 2000, 7 : 36 - 40
  • [9] Inflammation as a causative factor in the aetiology of Parkinson's disease
    Whitton, P. S.
    BRITISH JOURNAL OF PHARMACOLOGY, 2007, 150 (08) : 963 - 976
  • [10] The Idiopathic Parkinson's disease: A metabolic disease?
    Rieu, I.
    Boirie, Y.
    Morio, B.
    Derost, P.
    Ulla, M.
    Marques, A.
    Debilly, B.
    Bannier, S.
    Durif, F.
    REVUE NEUROLOGIQUE, 2010, 166 (10) : 822 - 828