Relationship Between Alcohol Consumption and Serum Lipid Profiles Among Middle-Aged Population in China: A Multiple-Center Cardiovascular Epidemiological Study

被引:23
作者
Hao, Guang [1 ,2 ]
Wang, Zengwu [1 ,2 ]
Zhang, Linfeng [1 ,2 ]
Chen, Zuo [1 ,2 ]
Wang, Xin [1 ,2 ]
Guo, Min [1 ,2 ]
Tian, Ye [1 ,2 ]
Shao, Lan [1 ,2 ]
Zhu, Manlu [1 ,2 ]
机构
[1] Peking Union Med Coll, Fuwai Hosp, Natl Ctr Cardiovasc Dis, Div Prevent & Community Hlth, Beijing 100037, Peoples R China
[2] Chinese Acad Med Sci, Beijing 100730, Peoples R China
关键词
alcohol; serum lipid; association; China; CORONARY-HEART-DISEASE; HIGH-DENSITY-LIPOPROTEIN; HDL-CHOLESTEROL; METABOLIC SYNDROME; RISK; MEN; TRIGLYCERIDES; METAANALYSIS; MORTALITY; ASSOCIATION;
D O I
10.1177/0003319714549557
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
We assessed the relationship between alcohol consumption and serum lipids in a middle-aged Chinese population. The overall prevalence of drinking among 10 154 participants was 34.07% in males and 3.61% in females. Heavy alcohol drinkers ( 30 g/d) tended to be older, smokers, hypertensive, do heavy physical activity, and have a lower body mass index. Levels of high-density lipoprotein cholesterol (HDL-C), apolipoprotein (apo) A1, low-density lipoprotein cholesterol-HDL-C ratio, and apo B-apo A1 ratio rose with increase in alcohol intake in males. An increase of 0.27 mmol/L in triglycerides and a decrease of 2.10 mg/dL in lipoprotein(a), Lp(a), were observed in male alcohol drinkers who consumed 30 g alcohol/d compared with abstainers after controlling for all confounders. Levels of total cholesterol, HDL-C, and apo A1 increased with increase in alcohol intake in both genders and Lp(a) decreased with the increase in alcohol intake in males.
引用
收藏
页码:753 / 758
页数:6
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