The Role of Energy in the Emergence of Biology from Chemistry

被引:19
作者
Dibrova, Daria V. [1 ,5 ]
Chudetsky, Michail Y. [2 ]
Galperin, Michael Y. [3 ]
Koonin, Eugene V. [3 ]
Mulkidjanian, Armen Y. [1 ,4 ,5 ]
机构
[1] Moscow MV Lomonosov State Univ, Sch Bioengn & Bioinformat, Moscow 119992, Russia
[2] Russian Acad Sci, Inst Oil & Gas Problems, Moscow 119991, Russia
[3] Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20894 USA
[4] Moscow MV Lomonosov State Univ, AN Belozersky Inst Physicochem Biol, Moscow 119992, Russia
[5] Univ Osnabruck, Sch Phys, D-49069 Osnabruck, Germany
来源
ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES | 2012年 / 42卷 / 05期
基金
俄罗斯基础研究基金会; 美国国家卫生研究院;
关键词
Bioenergetics; Cyclic nucleotides; ATP; Membrane potential; Evolution of membranes; Isoprenoid membranes; ADENOSINE-TRIPHOSPHATE; LIPID BILAYERS; ZINC-SULFIDE; METAL-IONS; ORIGIN; LIFE; EVOLUTION; CELLS; BIOSYNTHESIS; PHOSPHATES;
D O I
10.1007/s11084-012-9308-z
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Any scenario of the transition from chemistry to biology should include an "energy module" because life can exist only when supported by energy flow(s). We addressed the problem of primordial energetics by combining physico-chemical considerations with phylogenomic analysis. We propose that the first replicators could use abiotically formed, exceptionally photostable activated cyclic nucleotides both as building blocks and as the main energy source. Nucleoside triphosphates could replace cyclic nucleotides as the principal energy-rich compounds at the stage of the first cells, presumably because the metal chelates of nucleoside triphosphates penetrated membranes much better than the respective metal complexes of nucleoside monophosphates. The ability to exploit natural energy flows for biogenic production of energy-rich molecules could evolve only gradually, after the emergence of sophisticated enzymes and ion-tight membranes. We argue that, in the course of evolution, sodium-dependent membrane energetics preceded the proton-based energetics which evolved independently in bacteria and archaea.
引用
收藏
页码:459 / 468
页数:10
相关论文
共 75 条
[1]   THE PHOTOCHEMISTRY OF MANGANESE AND THE ORIGIN OF BANDED IRON FORMATIONS [J].
ANBAR, AD ;
HOLLAND, HD .
GEOCHIMICA ET COSMOCHIMICA ACTA, 1992, 56 (07) :2595-2603
[2]  
[Anonymous], 2011, ORIGINS LIFE PRIMAL
[3]  
[Anonymous], 1924, ORIGIN LIFE
[4]  
[Anonymous], 2006, SYSTEMS BIOL GENOMIC
[5]   Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation [J].
Barks, Hannah L. ;
Buckley, Ragan ;
Grieves, Gregory A. ;
Di Mauro, Ernesto ;
Hud, Nicholas V. ;
Orlando, Thomas M. .
CHEMBIOCHEM, 2010, 11 (09) :1240-1243
[6]  
Benner SA., 2006, RNA WORLD, V3rd
[7]   Origins and evolution of isoprenoid lipid biosynthesis in archaea [J].
Boucher, Y ;
Kamekura, M ;
Doolittle, WF .
MOLECULAR MICROBIOLOGY, 2004, 52 (02) :515-527
[8]   On the prebiotic potential of reduced oxidation state phosphorus: the H-phosphinate-pyruvate system [J].
Bryant, David E. ;
Marriott, Katie E. R. ;
Macgregor, Stuart A. ;
Kilner, Colin ;
Pasek, Matthew A. ;
Kee, Terence P. .
CHEMICAL COMMUNICATIONS, 2010, 46 (21) :3726-3728
[9]   Transient accumulation of elastic energy in proton translocating ATP synthase [J].
Cherepanov, DA ;
Mulkidjanian, AY ;
Junge, W .
FEBS LETTERS, 1999, 449 (01) :1-6
[10]   RNA decomposition by pyrite-induced radicals and possible role of lipids during the emergence of life [J].
Cohn, CA ;
Borda, MJ ;
Schoonen, MA .
EARTH AND PLANETARY SCIENCE LETTERS, 2004, 225 (3-4) :271-278