Recyclable fluorous organocatalysts promoted three-component reactions of pyruvate, aldehyde and amine at room temperature

被引：13
|
作者：
Qian, Jin-long [1 ]
Yi, Wen-bin [1 ]
Cai, Chun [1 ]
机构：
[1] Nanjing Univ Sci & Technol, Chem Engn Coll, Nanjing 210094, Jiangsu, Peoples R China
来源：
TETRAHEDRON LETTERS | 2013年 / 54卷 / 52期
基金：
中国国家自然科学基金;
关键词：
Fluorous organocatalyst; Pyrrol-2-ones; Multi-component reaction; EFFICIENT SYNTHESIS; DERIVATIVES;
D O I：
10.1016/j.tetlet.2013.10.058
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new fluorous imine carbothioate has been prepared as an organocatalyst for the synthesis of pyrrol-2-ones via the cyclo-condensation reaction of aldehydes, amines, and pyruvate at room temperature. The fluorous catalyst can be easily recovered from the reaction mixture by simple fluorous solid-phase extraction (F-SPE) and used for next run reaction without further purification. Crown Copyright (C) 2013 Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：7100 / 7102
页数：3
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