Secondary Metabolites and their Biological Activities from Endophytic Fungal Strain Aspergillus terreus XJA8 Associated with Vernonia anthelmintica

被引：6

作者：

Rustamova, Nigora ^{[1
,2
,4
]}

Bobakulov, Khayrulla ^{[5
]}

Litao, Niu ^{[1
,2
,3
]}

Nuerxiati, Rehebati ^{[1
,2
]}

Wali, Ahmidin ^{[1
,2
]}

Setzer, William N. ^{[6
]}

Yili, Abulimiti ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Reg, South Beijing Rd 40, Urumqi 830011, Xinjiang, Peoples R China

[2] Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plants, Urumqi 830011, Peoples R China

[3] Univ Chinese Acad Sci, Beijing 100039, Peoples R China

[4] Samarkand State Univ, Dept Biol, Univ Blvd 15, Samarkand 703004, Uzbekistan

[5] Acad Sci Uzbek, Inst Chem Plant Subst, Mirzo Ulugbek Str 77, Tashkent 100170, Uzbekistan

[6] Univ Alabama Huntsville, Dept Chem, Huntsville, AL 35899 USA

来源：

JOURNAL OF BIOLOGICALLY ACTIVE PRODUCTS FROM NATURE | 2022年 / 12卷 / 05期

基金：

中国科学院西部之光基金;

关键词：

Endophytic fungus; secondary metabolites; Aspergillus terreus XJA8; melanin synthesis; antimicrobial activity; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITIES; ACID; CONSTITUENTS; DERIVATIVES; PHYLOGENIES; INHIBITORS; DIVERSITY; LEAVES;

D O I：

10.1080/22311866.2022.2154265

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two isocoumarins (6-methoxymellein and 6-hydroxymellein), one pyrrole compound (minaline), one lactone derivative (butyrolactone II), five phenolic acids (phenylacetic, veratric (3,4-dimethoxybenzoic), 4-hydroxyphenylacetic, 4-hydroxybenzoic and protocatechuic acid), and two phenolic acid methyl esters ((2-hydroxyphenyl) acetic acid methyl ester and methyl 4-hydroxyphenylacetate), along with 1,3-bis(4-hydroxyphenyl) propan-2-one were isolated from the fungal strain Aspergillus terreus XJA8. The fungal strain was isolated from the root of the medicinal plant Vernonia anthelmintica for first time. All isolated secondary metabolites were evaluated for their antimicrobial activity and melanin synthesis in murine B16 cells.

引用

页码：421 / 435

页数：15

共 49 条

[1] New acorane sesquiterpenes isolated from the endophytic fungus Colletotrichum gloeosporioides SNB-GSSO7 [J].