Phenolics from strawberry cv. Falandi and their antioxidant and α-glucosidase inhibitory activities

被引:55
作者
Yang, Dan [1 ,2 ]
Xie, Haihui [1 ]
Jiang, Yueming [1 ]
Wei, Xiaoyi [1 ]
机构
[1] Chinese Acad Sci, Key Lab South China Agr Plant Mol Anal & Genet Im, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
关键词
Strawberry; Phenolic compounds; Structure determination; Antioxidant activity; alpha-Glucosidase inhibitory activity; FRAGARIA-ANANASSA; FRUIT; CONSTITUENTS; FLAVONOIDS; GLYCOSIDES; LIGNANS; ELLAGITANNIN; NEOLIGNAN; DUCH;
D O I
10.1016/j.foodchem.2015.08.091
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Three new phenolic glucosides, falandiosides A (1), B (2), and C (6) were isolated from strawberry (Fragaria x ananassa Duch.) cv. Falandi fruit, together with three flavone glucuronides (3-5), eleven lignan glycosides (12-22), and five others. Their structures were determined by spectroscopic methods. All the known phenolics were reported from strawberry for the first time. They were evaluated for antioxidant and alpha-glucosidase inhibitory activities. Three new and fifteen known phenolics showed potent 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical cation scavenging activity with IC50 values of 22.50-4.28 mu M in comparison to L-ascorbic acid (14.21 mu M). Quercetin 3-(6-methylglucuronide) (4), (+)-isolariciresinol 9'-glucoside (12), and (-)-isolariciresinol 9'-glucoside (13) were active in scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Moreover, compounds 12 and 13 had moderate ferric reducing antioxidant power (FRAP) values. Further, two new and seven known phenolics exhibited more potent alpha-glucosidase inhibitory activity with IC50 values of 537.43-25.39 mu M than acarbose (619.94 mu M). (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:857 / 863
页数:7
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