Amide bond formation via C(sp3)-H bond functionalization and CO insertion

被引：66

作者：

Liu, Huizhen ^{[1
]}

Laurenczy, Gabor ^{[1
]}

Yan, Ning ^{[1
]}

Dyson, Paul J. ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Inst Sci & Ingn Chim, CH-1015 Lausanne, Switzerland

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 03期

基金：

瑞士国家科学基金会;

关键词：

CATALYZED OXIDATIVE CARBONYLATION; H BONDS; ARYL HALIDES; AMIDATION; AMINOCARBONYLATION; PEPTIDES; ANILINE; ACIDS;

D O I：

10.1039/c3cc47015f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient method for the synthesis of amides via Pd-catalyzed oxidative carbonylation of C(sp(3))-H bonds with CO and amines is described. The route efficiently provides substituted phenyl amides from alkanes.

引用

页码：341 / 343

页数：3

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