Genes regulating the B cell receptor pathway are recurrently mutated in primary central nervous system lymphoma

被引：59

作者：

Montesinos-Rongen, Manuel ^{[1
]}

Schaefer, Ekaterine ^{[1
]}

Siebert, Reiner ^{[2
]}

Deckert, Martina ^{[1
]}

机构：

[1] Univ Hosp Cologne, Dept Neuropathol, D-50924 Cologne, Germany

[2] Univ Kiel, Inst Human Genet, Univ Hosp Schleswig Holstein, Kiel, Germany

来源：

ACTA NEUROPATHOLOGICA | 2012年 / 124卷 / 06期

关键词：

Primary Central Nervous System Lymphoma; Central Nervous System Lymphoma; Phosphatase Domain; Ship Gene; Pathway Deregulation;

D O I：

10.1007/s00401-012-1064-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：905 / 906

页数：2

共 8 条

[1] Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma [J].

Davis, R. Eric ;

Ngo, Vu N. ;

Lenz, Georg ;

Tolar, Pavel ;

Young, Ryan M. ;

Romesser, Paul B. ;

Kohlhammer, Holger ;

Lamy, Laurence ;

Zhao, Hong ;

Yang, Yandan ;

Xu, Weihong ;

Shaffer, Arthur L. ;

Wright, George ;

Xiao, Wenming ;

Powell, John ;

Jiang, Jian-Kang ;

Thomas, Craig J. ;

Rosenwald, Andreas ;

Ott, German ;

Muller-Hermelink, Hans Konrad ;

Gascoyne, Randy D. ;

Connors, Joseph M. ;

Johnson, Nathalie A. ;

Rimsza, Lisa M. ;

Campo, Elias ;

Jaffe, Elaine S. ;

Wilson, Wyndham H. ;

Delabie, Jan ;

Smeland, Erlend B. ;

Fisher, Richard I. ;

Braziel, Rita M. ;

Tubbs, Raymond R. ;

Cook, J. R. ;

Weisenburger, Dennis D. ;

Chan, Wing C. ;

Pierce, Susan K. ;

Staudt, Louis M. .

NATURE, 2010, 463 (7277) :88-U97

[2] Primary central nervous system lymphomas are derived from germinal-center B cells and show a preferential usage of the V4-34 gene segment [J].

Montesinos-Rongen, M ;

Küppers, R ;

Schlüter, D ;

Spieker, T ;

Van Roost, D ;

Schaller, C ;

Reifenberger, G ;

Wiestler, OD ;

Deckert-Schlüter, M .

AMERICAN JOURNAL OF PATHOLOGY, 1999, 155 (06) :2077-2086

[3] Primary diffuse large B-cell lymphomas of the central nervous system are targeted by aberrant somatic hypermutation [J].

Montesinos-Rongen, M ;

Van Roost, D ;

Schaller, C ;

Wiestler, OD ;

Deckert, M .

BLOOD, 2004, 103 (05) :1869-1875

[4] Activating L265P mutations of the MYD88 gene are common in primary central nervous system lymphoma [J].

Montesinos-Rongen, Manuel ;

Godlewska, Elzbieta ;

Brunn, Anna ;

Wiestler, Otmar D. ;

Siebert, Reiner ;

Deckert, Martina .

ACTA NEUROPATHOLOGICA, 2011, 122 (06) :791-792

[5] Mutations of CARD11 but not TNFAIP3 may activate the NF-κB pathway in primary CNS lymphoma [J].

Montesinos-Rongen, Manuel ;

Schmitz, Roland ;

Brunn, Anna ;

Gesk, Stefan ;

Richter, Julia ;

Hong, Ke ;

Wiestler, Otmar D. ;

Siebert, Reiner ;

Kueppers, Ralf ;

Deckert, Martina .

ACTA NEUROPATHOLOGICA, 2010, 120 (04) :529-535

[6] Primary lymphoma of the central nervous system: just DLBCL or not? [J].

Montesinos-Rongen, Manuel ;

Siebert, Reiner ;

Deckert, Martina .

BLOOD, 2009, 113 (01) :7-10

[7] Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma [J].

Morin, Ryan D. ;

Mendez-Lago, Maria ;

Mungall, Andrew J. ;

Goya, Rodrigo ;

Mungall, Karen L. ;

Corbett, Richard D. ;

Johnson, Nathalie A. ;

Severson, Tesa M. ;

Chiu, Readman ;

Field, Matthew ;

Jackman, Shaun ;

Krzywinski, Martin ;

Scott, David W. ;

Trinh, Diane L. ;

Tamura-Wells, Jessica ;

Li, Sa ;

Firme, Marlo R. ;

Rogic, Sanja ;

Griffith, Malachi ;

Chan, Susanna ;

Yakovenko, Oleksandr ;

Meyer, Irmtraud M. ;

Zhao, Eric Y. ;

Smailus, Duane ;

Moksa, Michelle ;

Chittaranjan, Suganthi ;

Rimsza, Lisa ;

Brooks-Wilson, Angela ;

Spinelli, John J. ;

Ben-Neriah, Susana ;

Meissner, Barbara ;

Woolcock, Bruce ;

Boyle, Merrill ;

McDonald, Helen ;

Tam, Angela ;

Zhao, Yongjun ;

Delaney, Allen ;

Zeng, Thomas ;

Tse, Kane ;

Butterfield, Yaron ;

Birol, Inanc ;

Holt, Rob ;

Schein, Jacqueline ;

Horsman, Douglas E. ;

Moore, Richard ;

Jones, Steven J. M. ;

Connors, Joseph M. ;

Hirst, Martin ;

Gascoyne, Randy D. ;

Marra, Marco A. .

NATURE, 2011, 476 (7360) :298-303

[8] Analysis of the coding genome of diffuse large B-cell lymphoma [J].

Pasqualucci, Laura ;

Trifonov, Vladimir ;

Fabbri, Giulia ;

Ma, Jing ;

Rossi, Davide ;

Chiarenza, Annalisa ;

Wells, Victoria A. ;

Grunn, Adina ;

Messina, Monica ;

Elliot, Oliver ;

Chan, Joseph ;

Bhagat, Govind ;

Chadburn, Amy ;

Gaidano, Gianluca ;

Mullighan, Charles G. ;

Rabadan, Raul ;

Dalla-Favera, Riccardo .

NATURE GENETICS, 2011, 43 (09) :830-U33

← 1 →