Bayesian Phylogenetics with BEAUti and the BEAST 1.7

被引:6509
作者
Drummond, Alexei J. [1 ,2 ]
Suchard, Marc A. [3 ,4 ,5 ]
Xie, Dong [1 ,2 ]
Rambaut, Andrew [6 ]
机构
[1] Univ Auckland, Dept Comp Sci, Auckland 1, New Zealand
[2] Univ Auckland, Allan Wilson Ctr Mol Ecol & Evolut, Auckland 1, New Zealand
[3] Univ Calif Los Angeles, David Geffen Sch Med, Dept Biomath, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, David Geffen Sch Med, Dept Human Genet, Los Angeles, CA 90095 USA
[5] Univ Calif Los Angeles, Sch Publ Hlth, Dept Biostat, Los Angeles, CA 90024 USA
[6] Univ Edinburgh, Inst Evolutionary Biol, Edinburgh, Midlothian, Scotland
基金
英国生物技术与生命科学研究理事会; 美国国家科学基金会; 英国惠康基金;
关键词
Bayesian phylogenetics; evolution; phylogenetics; molecular evolution; coalescent theory; SPECIES TREES; INFERENCE; HISTORY; CLOCKS; MODELS; TIME;
D O I
10.1093/molbev/mss075
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Computational evolutionary biology, statistical phylogenetics and coalescent-based population genetics are becoming increasingly central to the analysis and understanding of molecular sequence data. We present the Bayesian Evolutionary Analysis by Sampling Trees (BEAST) software package version 1.7, which implements a family of Markov chain Monte Carlo (MCMC) algorithms for Bayesian phylogenetic inference, divergence time dating, coalescent analysis, phylogeography and related molecular evolutionary analyses. This package includes an enhanced graphical user interface program called Bayesian Evolutionary Analysis Utility (BEAUti) that enables access to advanced models for molecular sequence and phenotypic trait evolution that were previously available to developers only. The package also provides new tools for visualizing and summarizing multispecies coalescent and phylogeographic analyses. BEAUti and BEAST 1.7 are open source under the GNU lesser general public license and available at http://beast-mcmc.googlecode.comandhttp://beast.bio.ed.ac.uk.
引用
收藏
页码:1969 / 1973
页数:5
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