Damage Control Surgery for Non-traumatic Abdominal Emergencies

被引:37
|
作者
Girard, Edouard [1 ,2 ,5 ]
Abba, Julio [1 ]
Boussat, Bastien [2 ,3 ]
Trilling, Bertrand [1 ,2 ]
Mancini, Adrian [1 ]
Bouzat, Pierre [4 ]
Letoublon, Christian [1 ]
Chirica, Mircea [1 ]
Arvieux, Catherine [1 ]
机构
[1] Grenoble Alpes Univ Hosp, Digest & Emergency Surg Dept, Grenoble, France
[2] Grenoble Alpes Univ, CNRS, TIMC Res Unit, Grenoble, France
[3] Grenoble Alpes Univ Hosp, Qual Care Unit, Grenoble, France
[4] Grenoble Alpes Univ Hosp, Anesthesiol & Intens Care Med, Grenoble, France
[5] Ctr Hosp Univ Grenoble Alpes, Hop Michallon, Serv Chirurg Digest & Gen, Blvd Chantourne, F-38700 Grenoble, La Tronche, France
关键词
CONTROL LAPAROTOMY; PANCREATIC SURGERY; INJURED PATIENTS; GENERAL-SURGERY; HEMORRHAGE; MANAGEMENT; CLASSIFICATION; COAGULOPATHY; OUTCOMES; SEPSIS;
D O I
10.1007/s00268-017-4262-6
中图分类号
R61 [外科手术学];
学科分类号
摘要
Damage control surgery (DCS) was a major paradigm change in the management of critically ill trauma patients and has gradually expanded in the general surgery arena, but data in this setting are still scarce. The study aim was to evaluate outcomes of DCS in patients with general surgery emergencies. Between 2005 and 2015, 164 patients (104 men, age 66) underwent DCS for non-traumatic abdominal emergencies. The decision to perform DCS was triggered by the presence of at least one trauma DCS criterion: hypotension (< 70 mmHg), hypothermia (< 35 A degrees C), acidosis (pH < 7.25), coagulopathy (INR ae<yen> 1.7) and massive (> 5 RBC) transfusion. Statistical tests were performed to identify risk factors for operative mortality. Observed outcomes were compared to those predicted by commonly employed scores (APACHE II, POSSUM, P-POSSUM, SAPS II). DCS was performed for acute mesenteric ischemia (n = 68), peritonitis (n = 44), pancreatitis (n = 28), bleeding (n = 14) and other (n = 10). Abdominal compartment syndrome was associated in 52 patients (32%). Seventy-four (45%) patients died and 150 patients (91%) experienced complications. On multivariate analysis, age (p = 0.018) and INR ae<yen> 1.7 (p = 0.001) were independent predictors of mortality. Mortality was 24% (13/55), 48% (22/46) and 62% (39/63) in patients with one, two and ae<yen>3 DCS criteria, respectively. Comparison of observed and score-predicted mortality suggested DCS use resulted in significant survival benefit of the whole cohort and of patients with pancreatitis and postoperative peritonitis. DCS can be lifesaving in critically ill patients with general surgery emergencies. Patients with peritonitis and acute pancreatitis are those who benefit most of the DCS approach.
引用
收藏
页码:965 / 973
页数:9
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