Necroptosis: A Specialized Pathway of Programmed Necrosis

被引：427

作者：

Galluzzi, Lorenzo ^{[1
,2
,3
]}

Kroemer, Guido ^{[1
,2
,3
]}

机构：

[1] INSERM, U848, F-94805 Villejuif, France

[2] Inst Gustave Roussy, F-94805 Villejuif, France

[3] Univ Paris 11, F-94270 Le Kremlin Bicetre, France

来源：

CELL | 2008年 / 135卷 / 07期

关键词：

D O I：

10.1016/j.cell.2008.12.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Necrosis is often viewed as an accidental and unregulated cellular event. However, accumulating evidence suggests that necrosis, like apoptosis, can be executed by regulated mechanisms. Hitomi et al. (2008) now describe an extensive network of genes that mediate a form of programmed necrosis called necroptosis.

引用

页码：1161 / 1163

页数：3

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