The study of sensitivity and precession of a single-source diffused tomography for detecting of target depth in biological phantom

Optical imaging can be used to study the cancerous stages of breast cancer; and this imaging is non-invasive and safe for healthy tissues. The key problem of optical imaging is the image reconstruction which depends on photon migration in biological tissues; because the study of photon migration in the biological tissues is a complicated problem. The diffusion equation is sometimes used to simulate the photon migration in the biological tissues. Due to limitation of diffusion equation and its approximated nature, we want to explore the accuracy and precision of this method. So in this study, we report the design of a single-source diffuse imaging system with simulating code based on finite element method (FEM) to detect the location of tumor in breast phantoms. The comparison between the reconstructed results and actual values can be considered as a criterion of accuracy of this diffused system. In this experimental setup, to reduce the expense of computational procedure, single source is applied, and the accuracy and precision of this single-source are investigated. (C) 2013 Elsevier GmbH. All rights reserved.