Identification of a Novel Inhibitor That Selectively Targets NF-κB Activity in KSHV-Infected Lymphoma Cells

被引：0
|
作者：
Nayar, Utthara [1 ]
Akar, Gunkut [1 ]
Shoemaker, Robert H. [2 ]
Sei, Shizuko [3 ]
Cesarman, Ethel [4 ]
机构：
[1] Weill Cornell Med Coll, New York, NY USA
[2] NCI, Div Canc Treatment & Diag, Frederick, MD 21701 USA
[3] NCI Frederick, Frederick, MD USA
[4] Cornell Univ, Weill Med Coll, New York, NY 10021 USA
来源：
BLOOD | 2012年 / 120卷 / 21期
关键词：
D O I：
10.1182/blood.V120.21.160.160
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
160
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Inhibition of NF-κB induces apoptosis of KSHV-infected primary effusion lymphoma cells
    Keller, SA
    Schattner, EJ
    Cesarman, E
    BLOOD, 2000, 96 (07) : 2537 - 2542
  • [2] Identification of Target Genes Regulated by KSHV miRNAs in KSHV-Infected Lymphoma Cells
    Quan, Liangliang
    Qiu, Tao
    Liang, Jiulong
    Li, Miao
    Zhang, Yu
    Tao, Kai
    PATHOLOGY & ONCOLOGY RESEARCH, 2015, 21 (04) : 875 - 880
  • [3] A novel NF-κB inhibitor DHMEQ selectively targets constitutive NF-κB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo
    Watanabe, M
    Dewan, Z
    Okamura, T
    Sasaki, M
    Itoh, K
    Higashihara, M
    Mizoguchi, H
    Honda, M
    Sata, T
    Watanabe, T
    Yamamoto, N
    Umezawa, K
    Horie, R
    INTERNATIONAL JOURNAL OF CANCER, 2005, 114 (01) : 32 - 38
  • [4] Targeting NF-κB and induction of apoptosis by novel NF-κB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) in Burkitt lymphoma cells
    Kimura, Noriko
    Miyakawa, Yoshitaka
    Kohmura, Kanoko
    Umezawa, Kazuo
    Ikeda, Yasuo
    Kizaki, Masahiro
    LEUKEMIA RESEARCH, 2007, 31 (11) : 1529 - 1535
  • [5] Constitutive NF-κB activity in KSHV infected primary effusion lymphomas.
    Keller, SA
    Schattner, EJ
    Cesarman, E
    BLOOD, 1999, 94 (10) : 302A - 302A
  • [6] Reactive Oxygen Species (ROS) are induced by vFLIP and regulate NF-kB activation in KSHV-infected primary effusion lymphoma cells
    Bubman, D
    Csernus, B
    Guasparri, I
    Cesarman, E
    BLOOD, 2005, 106 (11) : 291A - 291A
  • [7] Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA
    Lei, Xiufen
    Bai, Zhiqiang
    Ye, Fengchun
    Xie, Jianping
    Kim, Chan-Gil
    Huang, Yufei
    Gao, Shou-Jiang
    NATURE CELL BIOLOGY, 2010, 12 (02) : 193 - U232
  • [8] Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA
    Xiufen Lei
    Zhiqiang Bai
    Fengchun Ye
    Jianping Xie
    Chan-Gil Kim
    Yufei Huang
    Shou-Jiang Gao
    Nature Cell Biology, 2010, 12 : 193 - 199
  • [9] Selective Inhibition of Activated B-Cell Lymphoma Cells by a Novel Small Molecule Inhibitor of NF-κB
    Norton, John T.
    Hayashi, Tomoko
    Wu, Raymond P.
    Cottam, Howard
    Carson, Dennis A.
    BLOOD, 2011, 118 (21) : 1069 - 1069
  • [10] Erratum: Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA
    Xiufen Lei
    Zhiqiang Bai
    Fengchun Ye
    Jianping Xie
    Chan-Gil Kim
    Yufei Huang
    Shou-Jiang Gao
    Nature Cell Biology, 2010, 12 : 625 - 625
12345