Experimental gastric carcinogenesis related to Helicobacter pylori

被引:0
作者
Shimoyama, T [1 ]
Fukuda, Y [1 ]
Sakagami, T [1 ]
Yamamoto, N [1 ]
Kashihara, W [1 ]
Okui, M [1 ]
Tanida, N [1 ]
Tamura, G [1 ]
机构
[1] Hyogo Med Univ, Dept Gastroenterol, Nishinomiya, Hyogo 6638501, Japan
关键词
Helicobacter pylori; lipid A; gastric carcinogenesis; mongolian gerbil; mouse model;
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
In this paper, we present our research on the lipid A of Helicobacter pylori, an experimental study using the Mongolian gerbil model and experimental carcinogenesis using the mouse model to evaluate roles of host factors and bacterial factors which are related to the pathogenicity of Helicobacter pylori including gastric carcinogenesis. Future study on bacterial factors and host factors may give more insight into the role of Helicobacter pylori in gastric carcinogenesis.
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页码:1531 / 1536
页数:6
相关论文
共 21 条
[11]  
Lee A, 1998, GUT, V43, pA66
[12]   CELL-PROLIFERATION IN THE GASTRIC CORPUS IN HELICOBACTER-PYLORI-ASSOCIATED GASTRITIS AND AFTER GASTRIC RESECTION [J].
LYNCH, DAF ;
MAPSTONE, NP ;
CLARKE, AMT ;
JACKSON, P ;
DIXON, MF ;
QUIRKE, P ;
AXON, ATR .
GUT, 1995, 36 (03) :351-353
[13]   Immunobiological activities of chemically defined lipid a from Helicobacter pylori LPS in comparison with Porphyromonas gingivalis lipid a and Escherichia coli-type synthetic lipid A (compound 506) [J].
Ogawa, T ;
Suda, Y ;
Kashihara, W ;
Hayashi, T ;
Shimoyama, T ;
Kusumoto, S ;
Tamura, T .
VACCINE, 1997, 15 (15) :1598-1605
[14]   Atrophic gastric changes in both Helicobacter felis and Helicobacter pylori infected mice are host dependent and separate from antral gastritis [J].
Sakagami, T ;
Dixon, M ;
ORourke, J ;
Howlett, R ;
Alderuccio, F ;
Vella, J ;
Shimoyama, T ;
Lee, A .
GUT, 1996, 39 (05) :639-648
[15]  
SAKAGAMI T, 1997, IMMUNOLOGY CELL B S1, V75, pA18
[16]  
SHIMOYAMA T, 1997, PATHOGENESIS HOST RE, P186
[17]  
Suda Y, 1997, J BIOCHEM-TOKYO, V121, P1129
[18]  
Sugiyama A, 1998, CANCER RES, V58, P2067
[19]  
TAKADA H, 1992, BACTERIAL ENDOTOXIC, V1, P107
[20]   Induction of glandular stomach cancers in Helicobacter pylori-sensitive Mongolian gerbils treated with N-methyl-N-nitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine in drinking water [J].
Tatematsu, M ;
Yamamoto, M ;
Shimizu, N ;
Yoshikawa, A ;
Fukami, H ;
Kaminishi, M ;
Oohara, T ;
Sugiyama, A ;
Ikeno, T .
JAPANESE JOURNAL OF CANCER RESEARCH, 1998, 89 (02) :97-104