Making sense of the antisense transcripts in C9FTD/ALS

被引：1

作者：

Todd, Peter K. ^{[1
,2
]}

机构：

[1] Univ Michigan, Dept Neurol, Ann Arbor, MI 48109 USA

[2] Vet Hlth Adm Med Ctr, Ann Arbor, MI 48105 USA

来源：

ACTA NEUROPATHOLOGICA | 2013年 / 126卷 / 06期

关键词：

AMYOTROPHIC-LATERAL-SCLEROSIS; HEXANUCLEOTIDE REPEAT EXPANSION; PATHOLOGICAL FEATURES; C9ORF72; MUTATIONS; GGGGCC REPEAT; CHROMOSOME; 9P; NEURODEGENERATION; GENE; RNA; TRANSLATION;

D O I：

10.1007/s00401-013-1201-y

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：785 / 787

页数：3

共 25 条

[1] Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS [J].

Ash, Peter E. A. ;

Bieniek, Kevin F. ;

Gendron, Tania F. ;

Caulfield, Thomas ;

Lin, Wen-Lang ;

DeJesus-Hernandez, Mariely ;

van Blitterswijk, Marka M. ;

Jansen-West, Karen ;

Paul, Joseph W., III ;

Rademakers, Rosa ;

Boylan, Kevin B. ;

Dickson, Dennis W. ;

Petrucelli, Leonard .

NEURON, 2013, 77 (04) :639-646

[2]

Belzil VV, 2013, ACTA NEUROPATHOLOGIC

[3] Loss of Function of C9orf72 Causes Motor Deficits in a Zebrafish Model of Amyotrophic Lateral Sclerosis [J].

Ciura, Sorana ;

Lattante, Serena ;

Le Ber, Isabelle ;

Latouche, Morwena ;

Tostivint, Herve ;

Brice, Alexis ;

Kabashi, Edor .

ANNALS OF NEUROLOGY, 2013, 74 (02) :180-187

[4] Repeat-associated non-ATG (RAN) translation in neurological disease [J].

Cleary, John D. ;

Ranum, Laura P. W. .

HUMAN MOLECULAR GENETICS, 2013, 22 :R45-R51

[5] Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells [J].

Coffee, B ;

Zhang, FP ;

Warren, ST ;

Reines, D .

NATURE GENETICS, 1999, 22 (01) :98-101

[6] Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72 [J].

Cooper-Knock, Johnathan ;

Hewitt, Christopher ;

Highley, J. Robin ;

Brockington, Alice ;

Milano, Antonio ;

Man, Somai ;

Martindale, Joanne ;

Hartley, Judith ;

Walsh, Theresa ;

Gelsthorpe, Catherine ;

Baxter, Lynne ;

Forster, Gillian ;

Fox, Melanie ;

Bury, Joanna ;

Mok, Kin ;

McDermott, Christopher J. ;

Traynor, Bryan J. ;

Kirby, Janine ;

Wharton, Stephen B. ;

Ince, Paul G. ;

Hardy, John ;

Shaw, Pamela J. .

BRAIN, 2012, 135 :751-764

[7] Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS [J].

DeJesus-Hernandez, Mariely ;

Mackenzie, Ian R. ;

Boeve, Bradley F. ;

Boxer, Adam L. ;

Baker, Matt ;

Rutherford, Nicola J. ;

Nicholson, Alexandra M. ;

Finch, NiCole A. ;

Flynn, Heather ;

Adamson, Jennifer ;

Kouri, Naomi ;

Wojtas, Aleksandra ;

Sengdy, Pheth ;

Hsiung, Ging-Yuek R. ;

Karydas, Anna ;

Seeley, William W. ;

Josephs, Keith A. ;

Coppola, Giovanni ;

Geschwind, Daniel H. ;

Wszolek, Zbigniew K. ;

Feldman, Howard ;

Knopman, David S. ;

Petersen, Ronald C. ;

Miller, Bruce L. ;

Dickson, Dennis W. ;

Boylan, Kevin B. ;

Graff-Radford, Neill R. ;

Rademakers, Rosa .

NEURON, 2011, 72 (02) :245-256

[8] Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS [J].

Gendron, Tania F. ;

Bieniek, Kevin F. ;

Zhang, Yong-Jie ;

Jansen-West, Karen ;

Ash, Peter E. A. ;

Caulfield, Thomas ;

Daughrity, Lillian ;

Dunmore, Judith H. ;

Castanedes-Casey, Monica ;

Chew, Jeannie ;

Cosio, Danielle M. ;

van Blitterswijk, Marka ;

Lee, Wing C. ;

Rademakers, Rosa ;

Boylan, Kevin B. ;

Dickson, Dennis W. ;

Petrucelli, Leonard .

ACTA NEUROPATHOLOGICA, 2013, 126 (06) :829-844

[9] A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study [J].

Gijselinck, Ilse ;

Van Langenhove, Tim ;

van der Zee, Julie ;

Sleegers, Kristel ;

Philtjens, Stephanie ;

Kleinberger, Gernot ;

Janssens, Jonathan ;

Bettens, Karolien ;

Van Cauwenberghe, Caroline ;

Pereson, Sandra ;

Engelborghs, Sebastiaan ;

Sieben, Anne ;

De Jonghe, Peter ;

Vandenberghe, Rik ;

Santens, Patrick ;

De Bleecker, Jan ;

Maes, Githa ;

Baumer, Veerle ;

Dillen, Lubina ;

Joris, Geert ;

Cuijt, Ivy ;

Corsmit, Ellen ;

Elinck, Ellen ;

Van Dongen, Jasper ;

Vermeulen, Steven ;

Van den Broeck, Marleen ;

Vaerenberg, Carolien ;

Mattheijssens, Maria ;

Peeters, Karin ;

Robberecht, Wim ;

Cras, Patrick ;

Martin, Jean-Jacques ;

De Deyn, Peter P. ;

Cruts, Marc ;

Van Broeckhoven, Christine .

LANCET NEUROLOGY, 2012, 11 (01) :54-65

[10] Clinical and pathological features of familial frontotemporal dementia caused by C9ORF72 mutation on chromosome 9p [J].

Hsiung, Ging-Yuek R. ;

DeJesus-Hernandez, Mariely ;

Feldman, Howard H. ;

Sengdy, Pheth ;

Bouchard-Kerr, Phoenix ;

Dwosh, Emily ;

Butler, Rachel ;

Leung, Bonnie ;

Fok, Alice ;

Rutherford, Nicola J. ;

Baker, Matt ;

Rademakers, Rosa ;

Mackenzie, Ian R. A. .

BRAIN, 2012, 135 :709-722

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