Tandem Peterson-Michael reaction using alpha-silylalkylphosphine chalcogenides and Horner-Emmons reaction of in situ generated alpha-carban-ions of its products

被引：12

作者：

Kawashima, T

Nakamura, M

Inamoto, N

机构：

[1] Department of Chemistry, Graduate School of Science, University of Tokyo, Hongo, Bunkyo-ku

来源：

HETEROCYCLES | 1997年 / 44卷

关键词：

WITTIG REACTION; GAMMA-LACTONES; VINYLPHOSPHONATES; DERIVATIVES; RING;

D O I：

10.3987/COM-96-S49

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Title tandem reaction was achieved by using alpha-(trimethylsilyl)alkylphosphine chalcogenides and the lithio derivative of 2-hydroxytetrahydropyran. The Horner-Emmons reaction of the tandem products was accomplished to give the corresponding 2-(beta-styryl)tetrahydropyran derivatives by in situ generation and trapping of alpha-lithio derivatives, followed by Warren's method of olefination.

引用

收藏

页码：487 / 507

页数：21

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