An Emission Color-Changeable Sensor for Biothiol Using a Water-Soluble Conjugated Polymer in a Paper-Based Strip

被引：0
作者：
Jang, Geunseok [1 ]
Kim, Jongho [1 ]
Kim, Daigeun [1 ]
Lee, Taek Seung [1 ]
机构：
[1] Chungnam Natl Univ, Dept Adv Organ Mat & Text Syst Engn, Organ & Optoelect Mat Lab, Daejeon 305764, South Korea
来源：
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2016年 / 16卷 / 08期
基金：
新加坡国家研究基金会;
关键词：
Water-Soluble Conjugated Polymer; Fluorescence; Biothiol Detection; Paper-Based Sensor; FLUORESCENT SENSOR; SELECTIVE DETECTION; CHEMICAL SENSORS; CYSTEINE; HOMOCYSTEINE; GLUTATHIONE; POLYELECTROLYTE; SHIFT; PROBE;
D O I：
10.1166/jnn.2016.12488
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We investigated a paper-based sensor strip containing a water-soluble conjugated polymer (WSCP) for the detection of biothiols, including cysteine (Cys) and homocysteine (Hcy). The newly synthesized WSCP had triphenylamine groups with aldehyde pendants for interaction with the aminothiol group-containing amino acids such as Cys and Hcy to form five-and six-membered cyclic rings, respectively. We found that the paper-based sensor strip exhibited a visually noticeable fluorescence color change (violet-to-red) upon exposure to biothiols, mainly because of electronic changes in the polymer backbone via a reaction between the aldehyde group of the polymer and the aminothiol moiety in biothiol amino acids.
引用
收藏
页码：8728 / 8732
页数：5
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