Chemical etiology of nucleic acid structure

被引：452
作者：
Eschenmoser, A
机构：
[1] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA
[2] Swiss Fed Inst Technol, Organ Chem Lab, CH-8092 Zurich, Switzerland
来源：
SCIENCE | 1999年 / 284卷 / 5423期
关键词：
D O I：
10.1126/science.284.5423.2118
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Systematic chemical studies indicate that the capability of Watson-Crick base-pairing is widespread among potentially natural nucleic acid alternatives taken from RNA's close structural neighborhood. A comparison of RNA and such alternatives with regard to chemical properties that are fundamental to the biological function of RNA provides chemical facts that may contain clues to RNA's origin.
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页码：2118 / 2124
页数：7
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