Asymmetric mesoporous silica nanoparticles as potent and safe immunoadjuvants provoke high immune responses

被引：42
作者：
Abbaraju, Prasanna Lakshmi [1 ]
Jambhrunkar, Manasi [1 ]
Yang, Yannan [1 ]
Liu, Yang [1 ]
Lu, Yao [1 ]
Yu, Chengzhong [1 ]
机构：
[1] Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia
来源：
CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 16期
关键词：
GOLD NANOPARTICLES; VACCINE ADJUVANT; IN-VIVO; PEPTIDE; CELLS; NANOCOMPOSITES; ACTIVATION; MEMORY; SHAPE;
D O I：
10.1039/c8cc00327k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Asymmetric mesoporous silica nanoparticles with a head-tail structure are potent immunoadjuvants for delivering a peptide antigen, generating a higher antibody immune response in mice compared to their symmetric counterparts.
引用
收藏
页码：2020 / 2023
页数：4
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