Asymmetric mesoporous silica nanoparticles as potent and safe immunoadjuvants provoke high immune responses

被引：43

作者：

Abbaraju, Prasanna Lakshmi ^{[1
]}

Jambhrunkar, Manasi ^{[1
]}

Yang, Yannan ^{[1
]}

Liu, Yang ^{[1
]}

Lu, Yao ^{[1
]}

Yu, Chengzhong ^{[1
]}

机构：

[1] Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 16期

关键词：

GOLD NANOPARTICLES; VACCINE ADJUVANT; IN-VIVO; PEPTIDE; CELLS; NANOCOMPOSITES; ACTIVATION; MEMORY; SHAPE;

D O I：

10.1039/c8cc00327k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric mesoporous silica nanoparticles with a head-tail structure are potent immunoadjuvants for delivering a peptide antigen, generating a higher antibody immune response in mice compared to their symmetric counterparts.

引用

页码：2020 / 2023

页数：4

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