Work-up strategies for high-throughput solution synthesis

被引：21

作者：

Cork, D ^{[1
]}

Hird, N ^{[1
]}

机构：

[1] Takeda Chem Ind Ltd, Med Chem Res Labs 1, Div Pharmaceut Res, Yodogawa Ku, Osaka 5328686, Japan

来源：

DRUG DISCOVERY TODAY | 2002年 / 7卷 / 01期

关键词：

D O I：

10.1016/S1359-6446(01)02089-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The key bottleneck in parallel synthesis has, in truth, always been the isolation and purification of the reaction products, rather than carrying out the reactions themselves. Solution-phase chemistry for parallel synthesis has recently been re-emphasized and has stimulated the development of a wide-range of practical tools for efficient high-throughput work-up, which are gaining increasing acceptance in medicinal chemistry groups.

引用

页码：56 / 63

页数：8

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