Copper-catalyzed cyanation of arenes using benzyl nitrile as a cyanide anion surrogate

被引：109

作者：

Jin, Jisong ^{[1
]}

Wen, Qiaodong ^{[1
]}

Lu, Ping ^{[1
]}

Wang, Yanguang ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Zhejiang, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 79期

关键词：

C-H BONDS; AQUEOUS-SOLUTION; ARYL BROMIDES; ACTIVATION; OXIDATION; HALIDE; N; N-DIMETHYLFORMAMIDE; FUNCTIONALIZATIONS; PEROXIDE; IODIDES;

D O I：

10.1039/c2cc35046g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The copper-catalyzed cyanation of arenes using benzyl nitrile as a cyanide anion surrogate furnishes aromatic nitriles in moderate to good yields. The cascade process involves a copper-catalyzed aerobic C-H oxidation, a retro-cyanohydrination, and a copper-catalyzed aerobic oxidative C-H functionalization.

引用

页码：9933 / 9935

页数：3

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