Rational design, synthesis, and reactivity of lactendiynes, a new class of cyclic enediynes ortho-fused with the beta-lactam ring

被引：32

作者：

Banfi, L ^{[1
]}

Basso, A ^{[1
]}

Guanti, G ^{[1
]}

机构：

[1] CNR,CTR STUDIO CHIM COMPOSTI CICLOALIFATICI & AROMAT,I-16146 GENOA,ITALY

来源：

TETRAHEDRON | 1997年 / 53卷 / 09期

关键词：

D O I：

10.1016/S0040-4020(97)00036-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 10-membered cyclic enediynes trans-fused with N-protected and N-unprotecred beta-lactams have been stereoselectively prepared. These compounds were found to be stable toward Bergman cycloaromatization, which, on the other hand, takes place readily when the azetidinone ring is opened. (C) 1997 Elsevier Science Ltd.

引用

页码：3249 / 3268

页数：20

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