Zoonotic potential of Enterocytozoon bieneusi

被引:160
作者
Dengjel, B
Zahler, M
Hermanns, W
Heinritzi, K
Spillmann, T
Thomschke, A
Löscher, T
Gothe, R
Rinder, H
机构
[1] Univ Munich, Dept Trop Med & Infect Dis, D-80802 Munich, Germany
[2] Univ Munich, Inst Comparat Trop Med & Parasitol, D-80802 Munich, Germany
[3] Univ Munich, Inst Vet Pathol, D-80802 Munich, Germany
[4] Univ Munich, Clin Internal Med 2, D-80802 Munich, Germany
[5] Univ Giessen, Med & Forens Vet Clin 1, Giessen, Germany
关键词
D O I
10.1128/JCM.39.12.4495-4499.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The reservoirs and the modes of transmission of the most frequent microsporidial species in humans, Enterocytozoon bieneusi, are still unknown. We have examined fecal samples of 26 humans and 350 animals from 37 species to find 18 samples containing this parasite from humans, cats, pigs, cattle, and a llama. Genotypic characterization of the internal transcribed spacer of the rRNA gene resulted in 14 different genotypes, 6 of them previously undescribed. Phylogenetic analysis revealed the lack of a transmission barrier between E. bieneusi from humans and animals (cats, pigs, and cattle). Thus, E. bieneusi appears to be a zoonotic pathogen.
引用
收藏
页码:4495 / 4499
页数:5
相关论文
共 20 条
  • [1] High prevalence of Enterocytozoon bieneusi in swine with four genotypes that differ from those identified in humans
    Breitenmoser, AC
    Mathis, A
    Bürgi, E
    Weber, R
    Deplazes, P
    [J]. PARASITOLOGY, 1999, 118 : 447 - 453
  • [2] Modification of the clinical course of intestinal microsporidiosis in acquired immunodeficiency syndrome patients by immune status and anti-human immunodeficiency virus therapy
    Conteas, CN
    Berlin, OGW
    Speck, CE
    Pandhumas, SS
    Lariviere, MJ
    Fu, C
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1998, 58 (05) : 555 - 558
  • [3] Immunologic and molecular characteristics of Encephnlitozoon-like microsporidia isolated from humans and rabbits indicate that Encephalitozoon cuniculi is a zoonotic parasite
    Deplazes, P
    Mathis, A
    Baumgartner, R
    Tanner, I
    Weber, R
    [J]. CLINICAL INFECTIOUS DISEASES, 1996, 22 (03) : 557 - 559
  • [4] Molecular epidemiology of Encephalitozoon cuniculi and first detection of Enterocytozoon bieneusi in faecal samples of pigs
    Deplazes, P
    Mathis, A
    Muller, C
    Weber, R
    [J]. JOURNAL OF EUKARYOTIC MICROBIOLOGY, 1996, 43 (05) : S93 - S93
  • [5] DESPORTES I, 1985, J PROTOZOOL, V32, P250
  • [6] IDENTIFICATION AND CHARACTERIZATION OF 3 ENCEPHALITOZOON-CUNICULI STRAINS
    DIDIER, ES
    VOSSBRINCK, CR
    BAKER, MD
    ROGERS, LB
    BERTUCCI, DC
    SHADDUCK, JA
    [J]. PARASITOLOGY, 1995, 111 : 411 - 421
  • [7] Felsenstein J., 1993, PHYLIP PHYLOGENY INF
  • [8] CLUSTAL - A PACKAGE FOR PERFORMING MULTIPLE SEQUENCE ALIGNMENT ON A MICROCOMPUTER
    HIGGINS, DG
    SHARP, PM
    [J]. GENE, 1988, 73 (01) : 237 - 244
  • [9] Direct amplification and species determination of microsporidian DNA from stool specimens
    KatzwinkelWladarsch, S
    Lieb, M
    Heise, W
    Loscher, T
    Rinder, H
    [J]. TROPICAL MEDICINE & INTERNATIONAL HEALTH, 1996, 1 (03) : 373 - 378
  • [10] Transmission and serial propagation of Enterocytozoon bieneusi from humans and rhesus macaques in gnotobiotic piglets
    Kondova, I
    Mansfield, K
    Buckholt, MA
    Stein, B
    Widmer, G
    Carville, A
    Lackner, A
    Tzipori, S
    [J]. INFECTION AND IMMUNITY, 1998, 66 (11) : 5515 - 5519