Flow-injection method of spectrophotometric determination of catecholamines in pharmaceutical formulations

被引：5
|
作者：
Shpigun, L. K. [1 ]
Ryabenko, V. S. [1 ]
机构：
[1] Russian Acad Sci, NS Kurnakov Gen & Inorgan Chem Inst, Moscow 119991, Russia
来源：
THEORETICAL FOUNDATIONS OF CHEMICAL ENGINEERING | 2012年 / 46卷 / 04期
基金：
俄罗斯基础研究基金会;
关键词：
catecholamines; pharmaceutical analysis; flow-injection spectrophotometry; LIQUID-CHROMATOGRAPHY; DOPAMINE;
D O I：
10.1134/S0040579512040070
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
A simple, high-performing method of spectrophotometric determination of physiologically active catecholamines has been developed, which is based on the oxidation of these substances to the corresponding open-chain o-benzoquinones under the action of the hexachloroiridate (IV) or permanganate ion in a flow-injection system. The method has been successfully applied to the individual determination of catecholamines in pure forms and pharmaceutical formulations.
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页码：419 / 423
页数：5
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