Prevalence and patterns of renal involvement in imaging of malignant lymphoproliferative diseases

被引:26
作者
Bach, Andreas Gunter [1 ]
Behrmann, Curd [1 ]
Holzhausen, Hans Juergen [2 ]
Katzer, Michaela [3 ]
Arnold, Dirk [4 ]
Spielman, Rolf Peter [1 ]
Surov, Alexey [1 ]
机构
[1] Univ Halle Wittenberg, Dept Radiol, Halle, Germany
[2] Univ Halle Wittenberg, Dept Pathol, Halle, Germany
[3] Univ Halle Wittenberg, Dept Urol, Halle, Germany
[4] Univ Canc Ctr Hamburg, Hamburg, Germany
关键词
Lymphoma; urinary; CT; MR imaging; kidney; hematologic diseases; NON-HODGKINS-LYMPHOMA; MULTIPLE-MYELOMA; EXTRANODAL LYMPHOMA; ABDOMINAL MANIFESTATIONS; COMPUTED-TOMOGRAPHY; CT FEATURES; KIDNEY; SPECTRUM; LEUKEMIA; CHILDREN;
D O I
10.1258/ar.2011.110523
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Background: Renal involvement in patients with lymphoproliferative disease is an uncommon radiological finding. Purpose: To determine its prevalence and radiological appearances in a patient population. Material and Methods: All forms of lymphoproliferative disease (ICD: C81-C96) were considered. From January 2005 to January 2010, 668 consecutive patients with lymphoproliferative disease were identified with the help of the radiological database and patient records. Inclusion criteria were complete staging including appropriate CT scan and/or MRI. All stored images (initial staging and follow-up examinations) were reviewed. Results: Review of all stored images revealed renal infiltration in patients with non-Hodgkin lymphoma (11 of 364 = 3.0%; median age = 65 years, m:f = 6:5) but also multiple myeloma (2 of 162 = 1.2%; median age = 72 years; m:f = 1:1) and leukemia (5 of 101 = 4.9%; median age = 12 years; m:f = 2:3). There were no cases of renal infiltration in 41 patients with Hodgkin's disease. In total there were six patients with solitary lesions, five patients with diffuse renal enlargement, four patients with perirenal lesions, and two patients with direct invasion of the kidney. Conclusion: In leukemia the most common imaging pattern is diffuse enlargement. In the other subtypes of lymphoproliferative disease no specific correlation between typical CT patterns and subtype of lymphoproliferative disease can be found. The prevalence of renal involvement is in line with earlier studies. Contrary to earlier reports, multiple lesions were not found to be a common pattern.
引用
收藏
页码:343 / 348
页数:6
相关论文
共 42 条
[2]   Paraneoplastic glomerular diseases and malignancies [J].
Bacchetta, Justine ;
Juillard, Laurent ;
Cochat, Pierre ;
Droz, Jean-Pierre .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2009, 70 (01) :39-58
[3]  
BARCOS M, 1987, CANCER-AM CANCER SOC, V60, P827, DOI 10.1002/1097-0142(19870815)60:4<827::AID-CNCR2820600419>3.0.CO
[4]  
2-A
[5]   Abdominal Manifestations of Multiple Myeloma: A Retrospective Radiologic Overview [J].
Birjawi, Ghina A. ;
Jalbout, Rami ;
Musallam, Khaled M. ;
Tawil, Ayman N. ;
Taher, Ali T. ;
Khoury, Nabil J. .
CLINICAL LYMPHOMA & MYELOMA, 2008, 8 (06) :348-351
[6]   Renal involvement of non-Hodgkin's lymphoma and its prognostic effect in childhood [J].
Büyükpamukçu, M ;
Varan, A ;
Aydin, B ;
Kale, G ;
Akata, D ;
Yalçin, B ;
Akyüz, C ;
Kutluk, T .
NEPHRON CLINICAL PRACTICE, 2005, 100 (03) :C86-C91
[7]   CT of renal lymphoma in children [J].
Chepuri, NB ;
Strouse, PJ ;
Yanik, GA .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2003, 180 (02) :429-431
[8]   COMPUTED-TOMOGRAPHY OF RENAL LYMPHOMA [J].
COHAN, RH ;
DUNNICK, NR ;
LEDER, RA ;
BAKER, ME .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1990, 14 (06) :933-938
[9]   Kidney involvement and renal manifestations in non-Hodgkin's lymphoma and lymphocytic leukemia: a retrospective study in 700 patients [J].
Da'as, N ;
Polliack, A ;
Cohen, Y ;
Amir, G ;
Darmon, D ;
Kleinman, Y ;
Goldfarb, AW ;
Ben-Yehuda, D .
EUROPEAN JOURNAL OF HAEMATOLOGY, 2001, 67 (03) :158-164
[10]   LYMPHOMA OF THE KIDNEY - A REPORT OF 11 CASES [J].
FERRY, JA ;
HARRIS, NL ;
PAPANICOLAOU, N ;
YOUNG, RH .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1995, 19 (02) :134-144