A novel hybrid system for the fabrication of a fibrous mesh with micro-inclusions

被引:8
作者
Ahmad, Bilal [1 ]
Gunduz, Oguzhan [1 ,2 ]
Stoyanov, Simeon [3 ]
Pelan, Eddie [3 ]
Stride, Eleanor [1 ,4 ]
Edirisinghe, Mohan [1 ]
机构
[1] UCL, Dept Mech Engn, London WC1E 7JE, England
[2] Marmara Univ, Tech Educ Fac, Dept Mat, TR-34722 Istanbul, Turkey
[3] Unilever Res, NL-3130 AC Vlaardingen, Netherlands
[4] Univ Oxford, Inst Biomed Engn, Oxford OX3 7DQ, England
基金
英国工程与自然科学研究理事会;
关键词
Co-axial electrospinning; Microfluidics; Microbubbles; Particles; Fibrous mesh; TISSUE ENGINEERING APPLICATIONS; NANOFIBERS; POLYMER; CELLULOSE; SCAFFOLDS; DESIGN; FIBERS;
D O I
10.1016/j.carbpol.2012.02.074
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A novel hybrid system combining microfluidic and co-axial electrospinning techniques has been used to generate different types of fibre structures with varied desirable inclusions using food grade polymers, ethyl cellulose and sodium alginate. The processing conditions in the microfluidic T-junction device, i.e. gas pressure and liquid flow rate were adjusted in order to generate near-monodisperse microbubbles which subsequently serve as a platform for particle generation. These particles exhibit micro-scale diameters and different shapes and some bubbles were incorporated into the fibrous mesh prepared by concurrent electrospinning. The fibre/particle structures obtained with different polymers via this novel method could potentially have many applications in various engineering and biological sectors. (c) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:222 / 229
页数:8
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