Carbon-14 labelled Tribendimidine, a broad-spectrum anthelmintic drug

被引:2
作者
Fontana, Erminia [1 ,4 ]
Pignatti, Alberto [1 ]
Ghiglieri, Alberto [1 ]
Battaglia, Rosangela [1 ]
Cinato, Flavio [1 ]
Wang, Chong [2 ]
de Hostos, Eugenio [3 ]
机构
[1] Accelera Srl, I-20014 Nerviano, MI, Italy
[2] Shandong Xinhua Pharmaceut Co Ltd, Zibo, Shandong, Peoples R China
[3] OneWorld Hlth, San Francisco, CA USA
[4] Accelera Srl, Isotope Chem, I-20014 Nerviano, MI, Italy
关键词
tribendimidine; carbon-14; ADME; rat;
D O I
10.1002/jlcr.3070
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The preparation of [C-14]tribendimidine, a broad-spectrum anthelmintic agent related to amidantel, and its use during excretion and metabolism studies in the rat are described in this paper.
引用
收藏
页码:471 / 474
页数:4
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