Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair

被引：28
作者：
Al-Qattan, Mohammad M. [1 ]
Al-Shanawani, Bisher Nawras [1 ]
Alshomer, Feras [1 ]
机构：
[1] King Saud Univ, King Khalid Univ Hosp, Dept Surg, Plast & Recontruct Surg Unit, Riyadh 11415, Saudi Arabia
来源：
ANNALS OF SAUDI MEDICINE | 2013年 / 33卷 / 05期
关键词：
HYPERTROPHIC SCARS; INJECTIONS; GROWTH; PREDICTABILITY; PRESSURE; MUSCLES; PALATE; MODEL;
D O I：
10.5144/0256-4947.2013.482
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Botulinum toxin is a neurotoxin that has been utilized to induce chemo-denervation of muscles. Cutaneous wounds represent a special situation in which the tensile forces applied by these muscles on wound edges might have deleterious effects on the healing process. The aim of this review was to investigate such an effect and to review other mechanisms this toxin might have on the healing process. We also reviewed the role of botulinum toxin in the management of hypertrophic scars and cleft lip repair.
引用
收藏
页码：482 / 488
页数：7
相关论文
共 57 条
  • [21] Botulinum toxin to improve facial wound healing: A prospective, blinded, placebo-controlled study
    Gassner, Holger G.
    Brissett, Anthony E.
    Otley, Clark C.
    Boahene, Derek K.
    Boggust, Andy J.
    Weaver, Amy L.
    Sherris, David A.
    [J]. MAYO CLINIC PROCEEDINGS, 2006, 81 (08) : 1023 - 1028
  • [22] Gassner HG, 2009, ARCH FACIAL PLAST S, V11, P140, DOI 10.1001/archfacial.2009.3
  • [23] GONZALEZ-ULLOA M, 1956, Br J Plast Surg, V9, P212, DOI 10.1016/S0007-1226(56)80036-2
  • [24] GOZ G, 1987, SCAND J PLAST RECONS, V21, P31
  • [25] Effects of Botulinum Toxin A on Cytokine Synthesis in a Cell Culture Model of Cutaneous Scarring
    Haubner, Frank
    Ohmann, Elisabeth
    Mueller-Vogt, Uwe
    Kummer, Peter
    Strutz, Juergen
    Gassner, Holger
    [J]. ARCHIVES OF FACIAL PLASTIC SURGERY, 2012, 14 (02) : 122 - 126
  • [26] The use of botulinum toxin type A in cosmetic facial procedures
    Jaspers, G. W. C.
    Pijpe, J.
    Jansma, J.
    [J]. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2011, 40 (02) : 127 - 133
  • [27] Kane Michael A C, 2005, Facial Plast Surg, V21, P55, DOI 10.1055/s-2005-871764
  • [28] Larrabee Jr WF, 1995, PRINCIPLES FACIAL RE, P7
  • [29] Lebeda Frank J., 2012, J TOXICOLOGY
  • [30] Effect of Botulinum Toxin Type A on a Rat Surgical Wound Model
    Lee, Byung-Joo
    Jeong, Jae-Hwi
    Wang, Soo-Geun
    Lee, Jin-Choon
    Goh, Eui-Kyung
    Kim, Hwal-Woong
    [J]. CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY, 2009, 2 (01) : 20 - 27
123456