Probing trace Hg2+ in a microfluidic chip coupled with in situ near-infrared fluorescence detection

被引:9
|
作者
Wang, Jiaqin
Chen, Hui
Zhang, Peng
Zhang, Zhengyong
Zhang, Song
Kong, Jilie [1 ]
机构
[1] Fudan Univ, Dept Chem, CAM, Shanghai 200433, Peoples R China
基金
中国国家自然科学基金;
关键词
Near-infrared (NIR) fluorescence; Microfluidic chips; Single-walled carbon nanotubes (SWNTs); WALLED CARBON NANOTUBES; BAND-GAP FLUORESCENCE; CONTROLLED-RELEASE; DELIVERY;
D O I
10.1016/j.talanta.2013.03.079
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A novel microfluidic chip coupled with near-infrared (NIR) fluorescence detection set-up was established for specific analysis of trace Hg2+. Based on the NIR fluorescence changes caused by Hg2+-induced dissolution and aggregation of label-free single-strand DNA (ssDNA) wrapped single-walled carbon nanotubes (SWNTs), Hg2+ in aqueous solution were detected sensitively and specifically in the microfluidic chips system. Due to the small device dimension effect as well as the high efficiency of microfluidic chips, the reagent volume reduced from 500 mu L to 9 mu L and the minimum reaction time reaching the plateau was shortened from 60 min to 30 min, while the detection limit for Hg2+ decreased from 10.5 nM to 1.5 nM, compared with that of measured in regular Eppendorf tube. The idea of detecting NIR fluorescence spectra in microfluidic systems opens new avenues to optical analysis and bioassays in probing trace species. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:204 / 210
页数:7
相关论文
共 50 条
  • [21] Augmented microscopy with near-infrared fluorescence detection
    Watson, Jeffrey R.
    Martirosyan, Nikolay
    Skoch, Jesse
    Lemole, G. Michael, Jr.
    Anton, Rein
    Romanowski, Marek
    MOLECULAR-GUIDED SURGERY: MOLECULES, DEVICES, AND APPLICATIONS, 2015, 9311
  • [22] Bright far-red/near-infrared gold nanoclusters for highly selective and ultra-sensitive detection of Hg2+
    Zhang, Yan
    Jiang, Jingjing
    Li, Min
    Gao, Pengfei
    Shi, Lihong
    Zhang, Guomei
    Dong, Chuan
    Shuang, Shaomin
    SENSORS AND ACTUATORS B-CHEMICAL, 2017, 238 : 683 - 692
  • [23] In-situ and ultrasensitive detection of mercury (II) ions (Hg2+) using the localized surface plasmon resonance (LSPR) nanosensor and the microfluidic chip*
    Zhang, Wenjia
    Liu, Guohua
    Bi, Jinqiang
    Bao, Kexin
    Wang, Peiren
    SENSORS AND ACTUATORS A-PHYSICAL, 2023, 349
  • [24] Intelligent detection strategy and bioimaging application of dual-responsive Hg2+ and ONOO- using near-infrared probes
    Wang, Xiao
    Wang, Xuechuan
    Han, Qingxin
    ANALYTICA CHIMICA ACTA, 2023, 1266
  • [25] Dual-Probe SERS Chip: A Rapid and Ratiometric Detection of Trace Hg2+ in Food Samples
    Wan, Yuqi
    Li, Jingkun
    Jiang, Guoyong
    Qi, Junjie
    Pi, Fuwei
    ACS APPLIED NANO MATERIALS, 2025,
  • [26] Microfluidic chip for selective solid phase extraction of Pb2+ and Hg2+
    Zhang H.
    Liu X.
    Chuai R.
    Li X.
    Harbin Gongye Daxue Xuebao/Journal of Harbin Institute of Technology, 2017, 49 (05): : 141 - 147
  • [27] A Multi-Well SERS Chip for the Detection of Hg2+
    Xing, Xiaolu
    Zhang, Ying
    Tan, Yan
    Hu, Tianhao
    Chen, Ziqiu
    Liu, Bowen
    ACS APPLIED NANO MATERIALS, 2024, 7 (15) : 17287 - 17294
  • [28] Light Harvesting Nanoprobe for Trace Detection of Hg2+ in Water
    Chepak, Aleksandr
    Balatskiy, Denis
    Tutov, Mikhail
    Mironenko, Aleksandr
    Bratskaya, Svetlana
    MOLECULES, 2023, 28 (04):
  • [29] Self-Powered Sensor for Trace Hg2+ Detection
    Wen, Dan
    Deng, Liu
    Guo, Shaojun
    Dong, Shaojun
    ANALYTICAL CHEMISTRY, 2011, 83 (10) : 3968 - 3972
  • [30] A near-infrared BODIPY-based fluorescent probe for ratiometric and discriminative detection of Hg2+ and Cu2+ ions in living cells
    Huang, Yan
    Li, Chun-Feng
    Shi, Wen-Jing
    Tan, Hui-Ya
    He, Zhi-Zhou
    Zheng, Liyao
    Liu, Fenggang
    Yan, Jin-Wu
    TALANTA, 2019, 198 : 390 - 397