Cytotoxic Polyketides from a Marine-derived Fungus Aspergillus glaucus

被引：93
|
作者：
Du, Lin [1 ]
Zhu, Tianjiao [1 ]
Liu, Hongbing [1 ]
Fang, Yuchun [1 ]
Zhu, Weiming [1 ]
Gu, Qianqun [1 ]
机构：
[1] Ocean Univ China, Sch Med & Pharm, Chinese Minist Educ, Key Lab Marine Drugs, Qingdao 266003, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 11期
关键词：
D O I：
10.1021/np800303t
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Eight new aromatic polyketides (2, 4-6, 8, 14, 16, and 17) together with eight known analogues (3, 7, 9-13, and 15) were isolated from the marine-derived fungus Aspergillus glaucus. The structures and stereochemistry of the new compounds were elucidated by spectroscopic and chemical methods, and their cytotoxicities were evaluated against the HL-60 and A-549 cell lines.
引用
收藏
页码：1837 / 1842
页数：6
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