Association Between Chronic Kidney Disease and Blood Transfusions for Knee and Hip Arthroplasty Surgery

被引：33

作者：

Augustin, Ian D. ^{[1
]}

Yeoh, Tze Yeng ^{[1
]}

Sprung, Juraj ^{[1
]}

Berry, Daniel J. ^{[2
]}

Schroeder, Darrell R. ^{[3
]}

Weingarten, Toby N. ^{[1
]}

机构：

[1] Mayo Clin, Coll Med, Dept Anesthesiol, Rochester, MN 55905 USA

[2] Mayo Clin, Coll Med, Dept Orthoped Surg, Rochester, MN 55905 USA

[3] Mayo Clin, Coll Med, Dept Hlth Sci Res, Div Biostat & Informat, Rochester, MN 55905 USA

来源：

JOURNAL OF ARTHROPLASTY | 2013年 / 28卷 / 06期

关键词：

chronic kidney disease; total hip arthroplasty; total knee arthroplasty; blood transfusions; uremic bleeding; RECOMBINANT-HUMAN-ERYTHROPOIETIN; GLYCOPROTEIN-IIB-IIIA; RENAL-FAILURE; UREMIC PATIENTS; VONWILLEBRAND-FACTOR; ORTHOPEDIC-SURGERY; PLATELETS; ABNORMALITIES; DEFECT; CLASSIFICATION;

D O I：

10.1016/j.arth.2013.02.004

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

The study aim is to assess associations between chronic kidney disease (CKD) and blood transfusions during hospitalization for joint arthroplasty. Patients with Stage IV-V CKD who underwent elective total knee or hip arthroplasty from 2007 to 2010 were matched 2:1 with age, gender, and surgery type controls without kidney disease. Multivariable analyses for transfusion risk with preoperative hemoglobin, body mass index, cardiovascular disease, and surgical complexity as explanatory variables were performed. Ninety CKD patients were identified and had lower preoperative hemoglobin, higher incidence of cardiovascular disease and blood transfusions. CKD was independently associated with increased odds of transfusions (2.88, 95% confidence interval 1.33-6.23, P=0.007). Preoperative optimization of CKD patients should be considered to reduce transfusion rates. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：928 / 931

页数：4

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