Intraperitoneal sodium thiosulfate for the treatment of calciphylaxis

被引:51
|
作者
Mataic, Danijela [1 ]
Bastani, Bahar [1 ]
机构
[1] St Louis Univ, Sch Med, Dept Internal Med, Div Nephrol, St Louis, MO 63110 USA
关键词
sodium thiosulfate; calciphylaxis; calcific uremic arteriolopathy; peritoneal dialysis; end-stage renal disease;
D O I
10.1080/08860220600583781
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Calcific uremic arteriolopathy (or calciphylaxis) is a severe complication of renal failure characterized by subcutaneous calcification of the small arteries and tissue necrosis. We describe the case of a woman receiving continuous cycling peritoneal dialysis with calciphylaxis involving upper and lower extremities. After intolerance of intravenous sodium thiosulfate and limited intravenous access options, we administered sodium thiosulfate intraperitoneally and quantitated the amount of extra calcium removed. Intraperitoneal administration of sodium thiosulfate was well tolerated and led to removal of extra calcium with peritoneal dialysis.
引用
收藏
页码:361 / 363
页数:3
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