Transcranial magnetic stimulation (TMS) was applied over the frontal eye field (FEF) and the supplementary eye field (SEF) regions before execution of the first saccade in a double step task. When applied over the FEF, stimulation increased the percentage error in amplitude of the contralateral second saccade as compared to no stimulation. This was due to an interference with retinotopic but not craniotopic gain calculation. Stimulation of the SEF region interfered with saccade ordering. Thus, FEF might participate in target memorization whereas SEF is confirmed to code order information for sequential saccades even in this paradigm of only two consecutive movements. NeuroReport 13:253-255 (C) 2002 Lippincott Williams Wilkins.
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Natl Brain Res Ctr, Gurgaon 122051, Haryana, IndiaNatl Brain Res Ctr, Gurgaon 122051, Haryana, India
Sharika, K. M.
Neggers, Sebastiaan F. W.
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Univ Med Ctr Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, NetherlandsNatl Brain Res Ctr, Gurgaon 122051, Haryana, India
Neggers, Sebastiaan F. W.
Gutteling, Tjerk P.
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Univ Med Ctr Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, NetherlandsNatl Brain Res Ctr, Gurgaon 122051, Haryana, India
Gutteling, Tjerk P.
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Van der Stigchel, Stefan
Dijkerman, H. Chris
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Univ Utrecht, Helmholtz Inst, Dept Expt Psychol, NL-3584 CS Utrecht, NetherlandsNatl Brain Res Ctr, Gurgaon 122051, Haryana, India
Dijkerman, H. Chris
Murthy, Aditya
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Indian Inst Sci, Ctr Neurosci, Bengaluru 560012, Karnataka, IndiaNatl Brain Res Ctr, Gurgaon 122051, Haryana, India