Copper(I)-Catalyzed Cascade Sulfonimidate to Sulfonamide Rearrangement: Synthesis of Imidazo[1,2-a][1,4]diazepin-7(6H)-one

被引：24

作者：

Nagaraj, Muthupandi ^{[1
]}

Boominathan, Muthusamy ^{[1
]}

Perumal, Devanathan ^{[1
]}

Muthusubramanian, Shanmugam ^{[1
]}

Bhuvanesh, Nattamai ^{[2
]}

机构：

[1] Madurai Kamaraj Univ, Sch Chem, Dept Organ Chem, Madurai 625021, Tamil Nadu, India

[2] Texas A&M Univ, Dept Chem, Xray Diffract Lab, College Stn, TX 77842 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 77卷 / 14期

关键词：

ONE-POT SYNTHESIS; CATALYZED MULTICOMPONENT REACTION; TERMINAL ALKYNES; SULFONYL AZIDES; INTRAMOLECULAR ADDITION; ORGANIC-SYNTHESIS; ROOM-TEMPERATURE; AMIDE SYNTHESIS; FACILE ACCESS; KETENIMINES;

D O I：

10.1021/jo300855f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel strategy of copper(I)-catalyzed cascade intramolecular nucleophilic attack on N-sulfonylketenimine followed by rearrangement of sulfonirnidates to sulfonamides resulting in a library of substituted 8,9-dihydro-5H-imidazo[1,2-a]-[1,4]diazepin-7(6H)-ones has been developed.

引用

页码：6319 / 6326

页数：8

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