Two and three dimensional computer simulation of growth cancer

被引:3
作者
Ascencio, SF [1 ]
Meana, HP [1 ]
Miyatake, MN [1 ]
机构
[1] Natl Polytech Inst Mexico, Grad Sch, Mexico City 04430, DF, Mexico
来源
SCCC 2001: XXI INTERNATIONAL CONFERENCE OF THE CHILEAN COMPUTER SCIENCE SOCIETY, PROCEEDINGS | 2001年
关键词
D O I
10.1109/SCCC.2001.972634
中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
Perhaps the most destructive phenomena in natural science is the growth of cancer cells. The qualitative and quantitative comparison of simulated growth patterns with histological patterns of primary tumors may provide additional information about the morphology and the functional properties of cancer. In this paper we show a simple two and three dimensional model to simulate the growth of carcinoma. Our simulation includes cell proliferation, reciprocal influence among cells, cell division and cell death. The results show fractals structures and its gyration radius, number of cells on tumor periphery and fractal dimension, characterizes every simulated pattern growth. We proposes the use of Hash function to the DLA (Diffusion-Limited Aggregation) in two and three-dimensional problem, the possibility of developing studies in higher dimensions without affecting the required time by the algorithm, is shown. The similarities between this computational model and abnormal cell growing arc shown as well.
引用
收藏
页码:73 / 79
页数:7
相关论文
共 21 条
  • [1] ANDERSON JA, 1987, MUIRS TXB PATHOLOGY
  • [2] ASCENCIO SF, TELECOMMUNICATIONS R
  • [3] BASSINGTHWAIGHT.JB, 1994, FRACTAL PHYSL
  • [4] COOPERATIVE FORMATION OF CHIRAL PATTERNS DURING GROWTH OF BACTERIAL COLONIES
    BENJACOB, E
    COHEN, I
    SHOCHET, O
    TENENBAUM, A
    VICSEK, T
    CZIROK, A
    [J]. PHYSICAL REVIEW LETTERS, 1995, 75 (15) : 2899 - 2902
  • [5] GENERIC MODELING OF COOPERATIVE GROWTH-PATTERNS IN BACTERIAL COLONIES
    BENJACOB, E
    SCHOCHET, O
    TENENBAUM, A
    COHEN, I
    CZIROK, A
    VICSEK, T
    [J]. NATURE, 1994, 368 (6466) : 46 - 49
  • [6] TUMOR PROGRESSION AND THE NATURE OF CANCER
    CLARK, WH
    [J]. BRITISH JOURNAL OF CANCER, 1991, 64 (04) : 631 - 644
  • [7] Cotran R.S., 1994, Robbins pathologic basis of disease
  • [8] Eden M., 1960, 4TH P BERK S MATH ST, VIV, P223
  • [9] JULLIET R, AGGREGATION FRACTAL, P124
  • [10] JUNIOR SCF, 1998, PHYSICA A, V261, P569