Role of the Porphyromonas gingivalis InlJ protein in homotypic and heterotypic biofilm development

被引:47
作者
Capestany, CA [1 ]
Kuboniwa, M [1 ]
Jung, IY [1 ]
Park, Y [1 ]
Tribble, GD [1 ]
Lamont, RJ [1 ]
机构
[1] Univ Florida, Coll Dent, Dept Oral Biol, Gainesville, FL 32610 USA
关键词
D O I
10.1128/IAI.74.5.3002-3005.2006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The oral pathogen Porphyromonas gingivalis expresses a homolog of the internalin family protein InIJ. Inactivation of inlJ reduced monospecies biofilm formation by P. gingivalis. In contrast, heterotypic P. gingivalis-Streptococcus gordonii biofilm formation was enhanced in the InlJ-deficient mutant. The results indicate a nuanced role for InIJ in regulating biofilm accumulations of P. gingivalis.
引用
收藏
页码:3002 / 3005
页数:4
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