Gradient Moment Compensated Magnetic Resonance Spectroscopic Imaging

Spectroscopic imaging applications outside of the brain can suffer from artifacts due to inherent long scan times and susceptibility to motion. A fast spectroscopic imaging sequence has been devised with reduced sensitivity to motion. The sequence uses oscillating readout gradients and acquires k-space data in a spiral out-in fashion, which allows fast k-space coverage. We show that a spiral out-in readout acquisition is characterized by small gradient moments, reducing sensitivity to motion-induced artifacts. Data are acquired comparing the sequence to normal phase encoded spectroscopic imaging and conventional spiral spectroscopic Imaging protocols. In addition, in vivo data are acquired from the liver, demonstrating potential usage as a multivoxel fat/water spectroscopic Imaging tool. Results indicate that In the presence of motion, ghosting effects are reduced while metabolite signal increases of approximately 10% can be achieved. Magn Reson Med 61:457-461, 2009. (c) 2009 Wiley-Liss, Inc.