Polyvinylpolypyrrolidone-Supported Chlorosulfonic Acid: An Efficient Catalyst for One-Pot Synthesis of Dihydropyrimidinones and Octahydroquinazolin-2,5-diones

被引：8

作者：

Chegini, Masoumeh Goudarzvand ^{[1
]}

Mokhtary, Masoud ^{[1
]}

机构：

[1] Islamic Azad Univ, Rasht Branch, Dept Chem, POB 3516-41335, Rasht, Iran

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2017年 / 37卷 / 01期

关键词：

Chlorosulfonic acid; dihydropyrimidinones; octahydroquinazolin-2; 5-diones; polyvinylpolypyrrolidone; solvent-free condition; DERIVATIVES;

D O I：

10.1080/10406638.2015.1088046

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Polyvinylpolypyrrolidone-supported chlorosulfonic acid has been successfully applied to perform one-pot reaction of arylaldehydes, urea, ethylacetoacetate, or cyclic 1,3-diketo compounds under solvent-free condition at 70 degrees C to provide a series of dihydropyrimidinones and octahydroquinazolin-2,5-diones in good to excellent yields. The method offers several advantages such as high yield, short reaction time, simple workup, easy preparation, and reusability of the catalyst. The [PVPP-SO3H]Cl-+(-) catalyst was characterized via Fourier transform infrared spectroscopy (FT-IR) and thermal gravimetric analysis (TGA). Moreover, the catalyst could be recycled several times without significant loss of its catalytic activity. Clean methodologies, easy work-up procedure, high yield, and simple preparation of the catalyst are some advantages of this article.

引用

页码：63 / 72

页数：10

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