Global left ventricular longitudinal strain is associated with decreased melatonin levels in patients with acute myocardial infarction: a two-dimensional speckle tracking study

被引：11

作者：

Dominguez-Rodriguez, Alberto ^{[1
,2
,3
]}

Abreu-Gonzalez, Pedro ^{[3
,4
]}

Arroyo-Ucar, Eduardo ^{[1
]}

Avanzas, Pablo ^{[5
]}

Reiter, Russel J. ^{[6
]}

机构：

[1] Complejo Hosp Univ Canarias, Dept Cardiol, E-38320 Tenerife, Spain

[2] Univ Europea Canarias, Fac Ciencias Salud, Tenerife, Spain

[3] Inst Univ Tecnol Biomed, Tenerife, Spain

[4] Univ La Laguna, Dept Physiol, Tenerife, Spain

[5] Univ Oviedo, Hosp Cent Asturias, Dept Cardiol, E-33080 Oviedo, Spain

[6] Univ Texas Hlth Sci Ctr San Antonio, Dept Cellular & Struct Biol, San Antonio, TX 78229 USA

来源：

BIOMARKERS | 2013年 / 18卷 / 04期

关键词：

Echocardiography; melatonin; speckle tracking; ST-segment elevation myocardial infarction; OXIDATIVE STRESS; ECHOCARDIOGRAPHY; REPERFUSION; AXIS;

D O I：

10.3109/1354750X.2013.778330

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Low circulating melatonin levels predict poor outcome in patients with ST-segment elevation myocardial infarction (STEMI). In the present study, we investigated whether a relationship between myocardial deformation in parameters measured by echocardiography and circulating melatonin level exists. We prospectively included 112 patients with STEMI who performed echocardiography and simultaneous measurement of serum melatonin, during the light period within 72 h of admission. We found a negative correlation between circulating melatonin levels and global longitudinal strain (p = 0.006, r = -0.33). In conclusion, melatonin levels have a correlation with two-dimensional speckle tracking in patients with STEMI.

引用

页码：310 / 313

页数：4

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