Effect of amylin on the tone of rat aorta ring preparation

被引：6
作者：
Luk'yantseva, GV [1 ]
Sergeev, IY [1 ]
Kopylova, GN [1 ]
Samonina, GE [1 ]
German, SV [1 ]
机构：
[1] Moscow MV Lomonosov State Univ, Fac Biol, Dept Human & Anim Physiol, Moscow 117234, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2001年 / 132卷 / 04期
关键词：
amylin; rat aorta; vasodilation;
D O I：
10.1023/A:1013646723338
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Amylin (10(-10) M) induced relaxation of norepinephrine-precontracted rat aortic rings by more than 50%. This effect was preserved after blockade of NO-synthase and even after denudation of the vessel. Thus amylin-induced vasodilation is an endothelium-independent process not mediated by NO.
引用
收藏
页码：932 / 934
页数：3
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