OPINION e-Science: relieving bottlenecks in large-scale genome analyses

被引：13

作者：

Craddock, Tracy ^{[2
]}

Harwood, Colin R. ^{[1
]}

Hallinan, Jennifer ^{[2
]}

Wipat, Anil ^{[2
]}

机构：

[1] Newcastle Univ, Sch Med, Inst Cell & Mol Biosci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

[2] Newcastle Univ, Sch Comp Sci, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

NATURE REVIEWS MICROBIOLOGY | 2008年 / 6卷 / 12期

关键词：

D O I：

10.1038/nrmicro2031

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The development of affordable, high-throughput sequencing technology has led to a flood of publicly available bacterial genome-sequence data. The availability of multiple genome sequences presents both an opportunity and a challenge for microbiologists, and new computational approaches are needed to extract the knowledge that is required to address specific biological problems and to analyse genomic data. The field of e-Science is maturing, and Grid-based technologies can help address this challenge.

引用

页码：948 / U12

页数：8

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