Antiviral activity of the high-molecular-weight plant polysaccharides (Panavir®)

被引：17

作者：

Kalinina, Tatiana S. ^{[1
]}

Zlenko, Dmitry, V ^{[2
,4
]}

Kiselev, Aleksei, V ^{[4
]}

Litvin, Alexander A. ^{[3
]}

Stovbun, Sergey, V ^{[4
]}

机构：

[1] RAMS, VV Zakusov Inst Pharmacol, Moscow, Russia

[2] Moscow MV Lomonosov State Univ, Moscow, Russia

[3] Fed Res & Clin Ctr Phys Chem Med FMBA, Moscow, Russia

[4] Russian Acad Sci, NN Semenov Fed Res Ctr Chem Phys, Moscow, Russia

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2020年 / 161卷

关键词：

Antiviral activity; Immune modulator; COVID-19;

D O I：

10.1016/j.ijbiomac.2020.06.031

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This short report is dedicated to the description of the wide antiviral and antibacterial activity of the immune modulating agent Panavir (R). Panavir (R) is a high-molecular-weight fraction of the polysaccharides extracted from the shoots of the Solanum tuberosum. It demonstrates activity against many types of viruses, including animal coronavirus and also against bacterial infections. These properties look very promising considering the COVID-19 epidemy and allow propose that Panavir (R) would be effective in the therapy of the SARS-CoV-2 infection. (c) 2020 Elsevier B.V. All rights reserved.

引用

页码：936 / 938

页数：3

共 19 条

[1] Cha A. E., 2020, WASH POST
[2] The antiviral activity of polysaccharides and their derivatives
Chen, Ling
Huang, Gangliang
[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 115 : 77 - 82
[3] A New Symptom of COVID-19: Loss of Taste and Smell
Gautier, Jean-Francois
Ravussin, Yann
[J]. OBESITY, 2020, 28 (05) : 848 - 848
[4] Gribencha S. V., 2009, Antibiotiki i Khimioterapiya, V54, P31
[5] Study of antiparkinsonic activity of panavir on a model of Parkinson syndrome induced by systemic administration of MPTP to outbred rats and C57B1/6 mice
Kalinina, TS
Nerobkova, LN
Voronina, TA
Stovbun, SV
Litvin, AA
Sergienko, VI
[J]. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2005, 140 (01) : 55 - 57
[6] Kolbukhina L., 2009, CYTOKINES INFLAMMATI, V8, P49
[7] Kovchur P., 2011, B MSRU, V1, P24
[8] [Лепехин А.В. Lepekhin A.V.], 2007, [Инфекционные болезни, Infektsionnye bolezni], V5, P41
[9] Litvin A., 2012, CYTOKINES INFLAMMATI, V11, P123
[10] Martinez MJA, 2005, STUD NAT PROD CHEM, V30, P393

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