Halogen Dance and Sequential Cross-Coupling on 2-Anilinothiazoles

被引：8

作者：

Khan, Ather Farooq ^{[1
]}

Schnuerch, Michael ^{[1
]}

Mihovilovic, Marko D. ^{[1
]}

Stanetty, Peter ^{[1
]}

机构：

[1] Vienna Univ Technol, Inst Appl Synthet Chem, A-1060 Vienna, Austria

来源：

LETTERS IN ORGANIC CHEMISTRY | 2009年 / 6卷 / 02期

关键词：

Pd-catalysis; cross-couplings; thiazole; halogen dance; sequential cross-couplings; BIOLOGICAL EVALUATION; THIAZOLES; IMIDAZOLE; OXAZOLE;

D O I：

10.2174/157017809787582780

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 4-bromo-5-halo and 4-bromo-5-organometal-2-anilinothiazole derivatives were prepared via the halogen dance (HD) reaction. Subsequent Pd-catalyzed Stille and Suzuki-Miyaura cross-coupling reactions were performed in a sequential manner to obtain novel 4,5-diarylated-2-anilinothiazoles.

引用

页码：171 / 174

页数：4

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