Impact of a pediatric donation after cardiac death program

被引:35
作者
Pleacher, Kristine M. [1 ]
Roach, Elizabeth S. [2 ]
Van der Werf, Willem [3 ]
Antommaria, Armand H. M. [4 ]
Bratton, Susan L. [1 ]
机构
[1] Univ Utah, Dept Pediat, Div Pediat Crit Care, Salt Lake City, UT 84112 USA
[2] Intermt Donor Serv, Salt Lake City, UT USA
[3] Intermt Med Ctr, Dept Surg, Sect Abdominal Transplantat, Salt Lake City, UT USA
[4] Univ Utah, Dept Pediat, Div Inpatient Med & Med Eth, Salt Lake City, UT USA
关键词
death; tissue and organ procurement; infant; child; adolescent; ORGAN DONATION; LIVER-TRANSPLANTATION; EXPERIENCE; ATTITUDES; KIDNEY; DONORS; LIFE;
D O I
10.1097/PCC.0b013e318194800b
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Objectives: To determine the impact of a pediatric donation after cardiac death (DCD) program on organ donation. Design: Retrospective case series. Setting: A free-standing children's hospital. Patients: All ventilated pediatric intensive care unit patients who died between September 1, 2005 and April 30, 2007. Interventions: Institution of a DCD program. Measurements and Main Results: Data collected included clinical features, medical eligibility and consent for organ donation, as well as outcome for donation among eligible patients. One hundred ten patients who died in the pediatric intensive care unit and were treated with mechanical ventilation immediately before death were identified. Thirty-one patients met exclusion criteria, 26 patients were not referred, and 53 patients were evaluated for potential OCD by the organ procurement agency. The majority of patients had anoxia or trauma as their primary diagnosis. Family members initiated discussions regarding donation in 17% of evaluations. Sixty-eight percent of patients were deemed medically ineligible by the organ procurement agency. Of the 17 medically eligible patients, consent for donation was given in 9 cases (53%). Of these, 7 patients (41%) successfully donated; accounting for 37% of organ donors during the study period. Two families gave consent for donation which did not occur; one child did not die within the required time period and one could not be matched with any recipients. Conclusions: Although a small percentage of dying patients are eligible for and will undergo DCD, such a program can markedly increase the number of organ donors at a children's hospital. (Pediatr Crit Care Med 2009; 10:166-170)
引用
收藏
页码:166 / 170
页数:5
相关论文
共 30 条
[1]   Pediatric liver and kidney transplantation with allografts from DCD donors: A review of UNOS data [J].
Abt, Peter ;
Kashyap, Randeep ;
Orloff, Mark ;
Jain, Ashok ;
Tsoulfas, George ;
Bozorgzadeh, Adel ;
Olthoff, Kim .
TRANSPLANTATION, 2006, 82 (12) :1708-1711
[2]   Survival following liver transplantation from non-heart-beating donors [J].
Abt, PL ;
Desai, NM ;
Crawford, MD ;
Forman, LM ;
Markmann, JW ;
Olthoff, KM ;
Markmann, JF .
ANNALS OF SURGERY, 2004, 239 (01) :87-92
[3]  
*AM MED ASS, ORG PROC FOLL CARD D
[4]  
[Anonymous], 1987, CAN MED ASSOC J, V136, pA200
[5]  
[Anonymous], ORGAN PROCUREMENT TR
[6]   Individual choice in the definition of death [J].
Bagheri, A. .
JOURNAL OF MEDICAL ETHICS, 2007, 33 (03) :146-149
[7]   Report of a national conference on donation after cardiac death [J].
Bernat, JL ;
D'Alessandro, AM ;
Port, FK ;
Bleck, TP ;
Heard, SO ;
Medina, J ;
Rosenbaum, SH ;
DeVita, MA ;
Gaston, RS ;
Merion, RM ;
Barr, ML ;
Marks, WH ;
Nathan, H ;
O'Connor, K ;
Rudow, DL ;
Leichtman, AB ;
Schwab, P ;
Ascher, NL ;
Metzger, RA ;
Mc Bride, V ;
Graham, W ;
Wagner, D ;
Warren, J ;
Delmonico, FL .
AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (02) :281-291
[8]  
Berner ME, 2006, SWISS MED WKLY, V136, P597
[9]   Circumstances surrounding the deaths of hospitalized children: Opportunities for pediatric palliative care [J].
Carter, BS ;
Howenstein, M ;
Gilmer, MJ ;
Throop, P ;
France, D ;
Whitlock, JA .
PEDIATRICS, 2004, 114 (03) :E361-E366
[10]   Pediatric staff perspectives on organ donation after cardiac death in children [J].
Curley, Martha A. Q. ;
Harrison, Charlofte H. ;
Craig, Nancy ;
Lillehei, Craig W. ;
Micheli, Anne ;
Laussen, Peter C. .
PEDIATRIC CRITICAL CARE MEDICINE, 2007, 8 (03) :212-219