Combined DCE and DW-MRI in the diagnosis of benign and malignant tumors of the tongue

被引：13

作者：

Ai, Songtao ^{[1
]}

Zhu, Wenjing ^{[1
]}

Liu, Yu ^{[1
]}

Wang, Pingzhong ^{[1
]}

Yu, Qiang ^{[1
]}

Dai, Kerong ^{[2
]}

机构：

[1] Shanghai Jiao Tong Univ, Deportment Radiolog, Shanghai Peoples Hosp 9, Sch Med, Shanghai 200030, Peoples R China

[2] Shanghai Jiao Tong Univ, Dept Orthopaed, Engn Res Ctr Digital Med, Sch Med,Minist Educ,Peoples Hosp 9, Shanghai 200030, Peoples R China

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2013年 / 18卷

关键词：

Diffusion; Dynamic; enhancement; MRI; Tongue; Tumor; APPARENT DIFFUSION-COEFFICIENT; CONTRAST-ENHANCED MRI; SQUAMOUS-CELL CARCINOMA; PAROTID-GLAND; HEAD; LESIONS; MALFORMATIONS; ACCURACY; LYMPHOMA; MASSES;

D O I：

10.2741/4166

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The combination of dynamic contrast-enhanced (DCE) and diffusion-weighted (DW)-MRI adds important information to the findings obtained through conventional spin echo MRI. We aimed to determine the value of combined DW- and DCE-MRI in distinguishing benign from malignant tumors of the tongue and mouth floor. The apparent diffusion coefficient (ADC) maps were constructed, and the ADC values of the lesions were calculated from DW-MRI. The slopes were derived from time-intensity curves (TICs) from DCE-MRI. The ADC map for malignant tumors was lower compared with the benign lesions. The slope in the malignant tumors was significantly greater compared with the benign lesions. In malignant tumors, the ADC(b=500) threshold of <1.43x10(-3) mm(2)/s yielded a sensitivity, specificity, and accuracy of 74.6%, 83.3%, and 79.7%, respectively. For benign lesions, a slope threshold of <38.6 yielded a sensitivity, specificity, and accuracy of 80.3%, 74.5%, and 77.9%, respectively. Combined DCE- and DW-MR imaging may provide valuable information that allows for the differentiation between benign lesions and malignant tumors of the tongue and mouth floor.

引用

页码：1098 / 1111

页数：14