Dde as a protecting group for carbohydrate synthesis

被引：8

作者：

Bornaghi, L

Dekany, G

Drinnan, NB

Taylor, S

Toth, I

West, ML

机构：

[1] Alchemia Pty Ltd, Mt Gravatt, Qld 4122, Australia

[2] Univ Queensland, Dept Pharm, St Lucia, Qld, Australia

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 2006年 / 25卷 / 01期

关键词：

carbohydrates; vinylogous amides; protecting group;

D O I：

10.1080/07328300500388685

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Oligosaccharide synthesis using aminosugars requires the presence of a suitable amino protecting group. A number of protecting groups are currently used, and while many display favorable properties, most agents available still suffer from certain disadvantages. This report details the use of a hydrazine labile aminosugar protecting group, N -[1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl] (Dde), which can be introduced and removed in a facile and cost-effective manner.

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页码：1 / 18

页数：18

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