Intestinal endometriosis complicated by ileal perforation after initiation of gonadotropin-releasing hormone agonist therapy

被引:9
作者
Saito, Sayaka
Murakami, Takashi [1 ]
Suzuki, Kichiya
Terada, Yukihiro
Fukushima, Kouhei [2 ]
Moriya, Takuya [3 ]
机构
[1] Tohoku Univ, Grad Sch Med, Dept Obstet & Gynaecol, Aoba Ku, Sendai, Miyagi 9808574, Japan
[2] Tohoku Univ, Grad Sch Med, Dept Surg, Sendai, Miyagi 9808574, Japan
[3] Tohoku Univ, Grad Sch Med, Dept Pathol, Sendai, Miyagi 9808574, Japan
关键词
Bowel endometriosis; GnRH agonist; complication;
D O I
10.1016/j.fertnstert.2006.12.082
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To report a rare complication of GnRH agonist therapy for intestinal endometriosis. Design: Case report. Setting: University hospital. Patient(s): A 45-year-old nulliparous Japanese woman with catamenial digestive symptoms. Intervention(s): GnRH agonist therapy. Main Outcome Measure(s): Acute abdomenal crisis with free air in the abdominal X-ray. Result(s): An emergency laparotomy showed both an ileal constriction and perforation. An ileocecal enterectomy with an end-to-end anastomosis was performed. A pathological examination of the ileum revealed ileal endometriosis. Conclusion(s): Flare-up of intestinal endometriosis induced by GnRH agonist has the potential to lead to intestinal perforation. Careful diagnosis and treatment are necessary for cyclic and periodic gastrointestinal manifestation. (Fertil Steril (R) 2007;88:969.e7-9. (c) 2007 by American Society for Reproductive Medicine.)
引用
收藏
页码:969.e7 / 969.e9
页数:3
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